ksmaКубанский научный медицинский вестникKuban Scientific Medical Bulletin1608-62282541-9544Kuban State Medical University10.25207/1608-6228-2019-26-2-214-223ksma-1720Research ArticleОБЗОРЫREVIEWХАРАКТЕРИСТИКА ВИРУСА ЭНЦЕФАЛОМИОКАРДИТА И ЕГО ЗООНОЗНЫЙ ПОТЕНЦИАЛ (ОБЗОР ЛИТЕРАТУРЫ) ЧАСТЬ I. СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ О СТРОЕНИИ, СТРУКТУРЕ, ЖИЗНЕННОМ ЦИКЛЕ ВИРУСАTHE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A Literature Review) PART I. MODERN VIEWS ON THE EMCV STRUCTURE AND ITS VIRAL CYCLEКалайджянА. А.KalajdzhjanAkop A.

аспирант лаборатории молекулярной биологии,

ул. Мира, д. 177, г. Сочи, 354376

PhD Researcher, Laboratory of Molecular Biology,

Mira str., 177, Sochi, 354376

КадеА. Х.KadeAzamat Kh.

доктор медицинских наук, профессор, заведующий кафедрой общей и клинической патологической физиологии,

ул. им. Митрофана Седина, д. 4, г. Краснодар, 350063

Dr. Sci. (Med.), Prof., Head of Department, Department of General and Clinical Pathological Physiology,

Mitrofanа Sedinа str., 4, Krasnodar, 350063

ПоляковП. П. PolyakovPavel P.

ассистент кафедры общей и клинической патологической физиологии,

ул. им. Митрофана Седина, д. 4, г. Краснодар, 350063

Research Assistant, Department of General and Clinical Pathological Physiology,

Mitrofanа Sedinа str., 4, Krasnodar, 350063

pal.pal.p@yandex.ruГудмановаА. И.GudmanovaAlla A.

врач-терапевт,

ул. Айвазовского, д. 97, г. Краснодар, 350040

Physician,

Aivazovskogo str., 97, Krasnodar, 350040

Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт медицинской приматологии»РоссияScientific Research Institute of Medical PrimatologyRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияKuban State Medical University, Ministry of Healthcare of the Russian FederationRussian FederationГосударственное бюджетное учреждение здравоохранения «Городская клиническая больница № 3 города Краснодара» Министерства здравоохранения Краснодарского краяРоссияKrasnodar City Clinical Hospital No. 3, Ministry of Healthcare of Krasnodar KraiRussian Federation201917052019262214223Copyright © Калайджян А.А., Каде А.Х., Поляков П.П., Гудманова А.И., 20192019Калайджян А.А., Каде А.Х., Поляков П.П., Гудманова А.И.Kalajdzhjan A.A., Kade A.K.,  Polyakov P.P., Gudmanova A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ksma.elpub.ru/jour/article/view/1720

В настоящее время нередко регистрируются вспышки заболевания людей типичными зоонозными инфекциями, ранее встречавшимися исключительно в ветеринарной практике, например оспой обезьян (весна 2003 года в США — первое зарегистрированное появление болезни за пределами африканского континента). Важным фактором, способствующим проникновению инфекций в человеческую популяцию, является тесный контакт людей с представителями фауны на фоне интенсивно разрастающихся городов, что обусловливает актуальность изучения все новых зоонозных заболеваний, потенциально опасных для человека. Так, в результате ретроспективных исследований населения Перу от 2009 года установлены случаи инфицирования вирусом энцефаломиокардита (ЭМКВ) (семейство Picornaviridae, род Cardiovirus) людей, перенесших острое лихорадочное заболевание. Новый штамм вируса, принадлежащего тому же роду, был описан в ходе вспышки среди приматов питомника обезьян в 1990–1999 годах в городе Сухум (Республика Абхазия), а также выделен в ходе вспышки среди обезьян приматологического центра на территории Краснодарского края в 2012 году. Все это послужило поводом для написания обзора накопленных данных, отражающего строение, структуру, факторы вирулентности и распространение ЭМКВ.

There have been a growing number of the outbreaks of human diseases with typical zoonotic infections, which have previously occurred exclusively in veterinary practice. Among them is monkeypox, whose first occurrence outside the African continent was registered in the USA in the spring of 2003. An important factor contributing to the penetration of infections into the human population is a close contact of people with fauna representatives in the context of intensively growing cities. Therefore, research into new zoonotic diseases, which are potentially dangerous to humans, seems to be critically important. Thus, retrospective studies carried out among the Peru population in 2009 revealed the cases of the encephalomyocarditis virus (EMCV) (Picornaviridae family, Cardiovirus genus) infection in people having suffered from acute febrile illness. A new virus strain belonging to the same genus was described during the infection outbreak among primates of the Sukhumi Monkey nursery (Republic of Abkhazia) in 1990–1999. This strain was also identified during the outbreak among the monkeys of the Primatological Centre in the Krasnodar Krai in 2012. In this review, we generalize the data available on the structure, virulence factors and distribution of EMCV.

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The authors declare that there are no conflicts of interest present.