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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ksma</journal-id><journal-title-group><journal-title xml:lang="ru">Кубанский научный медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Kuban Scientific Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1608-6228</issn><issn pub-type="epub">2541-9544</issn><publisher><publisher-name>Kuban State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25207/1608-6228-2019-26-3-33-40</article-id><article-id custom-type="elpub" pub-id-type="custom">ksma-1778</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES. CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>СРАВНЕНИЕ ФРАКЦИИ ВЫБРОСА И КОНЕЧНЫХ ОБЪЕМОВ ЛЕВОГО ЖЕЛУДОЧКА КАК ПОКАЗАТЕЛЕЙ ТЯЖЕСТИ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ</article-title><trans-title-group xml:lang="en"><trans-title>COMPARISON OF EJECTION FRACTION AND END VOLUMES OF THE LEFT VENTRICLE AS INDICATORS OF THE SEVERITY OF HEART FAILURE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Газизова</surname><given-names>Д. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Gazizova</surname><given-names>Dinara Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, главный научный сотрудник лаборатории «Математическое моделирование и мониторинг»,</p><p>Рублевское шоссе, д. 135, г. Москва, 121552;</p><p>тел.: +7 (495) 414-75-52, +7 (916) 188-14-51</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Principal Researcher, Laboratory of Mathematical Modelling and Monitoring,</p><p>Roublyevskoe Shosse, 135, Moscow, 121552;</p><p>tel.: +7 (495) 414-75-52, +7 (916) 188-14-51</p></bio><email xlink:type="simple">dgazizova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр сердечно-сосудистой хирургии им. А.Н. Бакулева» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>05</day><month>07</month><year>2019</year></pub-date><volume>26</volume><issue>3</issue><fpage>33</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Газизова Д.Ш., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Газизова Д.Ш.</copyright-holder><copyright-holder xml:lang="en">Gazizova D.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ksma.elpub.ru/jour/article/view/1778">https://ksma.elpub.ru/jour/article/view/1778</self-uri><abstract><p>Цель — показать, что конечные объемы отражают тяжесть патологического состояния левого желудочка не только при сохраненной, но и при низкой фракции выброса. Материалы и методы. Исследованы 32 больных дилатационной кардиомиопатией с выраженной сердечной недостаточностью и полным мониторно-компьютерным и эхокардиографическим контролем. Результаты. Исследована чувствительность фракции выброса и конечных объемов к выраженности изменения функции сердца (ударный индекс от 15,3 до 57,2 и в среднем 29,5±1,6; фракция выброса от 16,5 до 48,0, в среднем 27,4±1,0; частота сердечных сокращений от 52 до 113, в среднем 81,8±2,4). Оказалось, что процентное изменение (чувствительность) фракции выброса (на 55%) значительно ниже, чем чувствительность индекса конечного диастолического объема (190%) и индекса конечного систолического объема (438%) к выраженности сердечной недостаточности. Заключение. Индексы конечного диастолического и конечного систолического объемов тяжелых больных дилатационной кардиомиопатией с низкой фракцией выброса более чувствительны к выраженности сердечной недостаточности, чем фракция выброса. Поэтому целесообразно использовать конечные объемы в качестве показателей сердечной недостаточности. Адекватная количественная оценка тяжести сердечной недостаточности должна включать частоту сердечных сокращений (длительность сердечного цикла).</p></abstract><trans-abstract xml:lang="en"><p>Aim. To demonstrate that the end volumes are indicative of the severity of the left ventricle pathological condition not only under preserved, but also under reduced ejection fraction. Material and methods. 32 patients with dilated cardiomyopathy and severe heart failure, as well as with complete monitor and computer and echocardiographic control were examined. Results. The sensitivity of the ejection fraction and end volumes to the severity of heart failure (stroke index from 15.3 to 57.2, average 29.5±1.6; ejection fraction from 16.5 to 48.0, average 27.4±127; heart rate from 52 tо 113, average 81.8±2.4) was established. It is shown that the percentage change (sensitivity) of the ejection fraction (55%) is much lower than that of the end diastolic volume index (190%) and that of the end systolic volume index (438%) to the severity of heart failure. Conclusion. Indices of end-diastolic and end-systolic volumes of critical patients with dilated cardiomyopathy are more sensitive to the severity of heart failure than the ejection fraction. It is advisable to use end volumes as indicators of heart failure. An adequate quantitative assessment of the severity of heart failure should include the heart rate (duration of the cardiac cycle T).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечная недостаточность</kwd><kwd>левый желудочек</kwd><kwd>фракция выброса</kwd><kwd>конечный систолический объем</kwd><kwd>конечный диастолический объем</kwd><kwd>частота сердечных сокращений</kwd></kwd-group><kwd-group xml:lang="en"><kwd>critical heart failure</kwd><kwd>left ventricle</kwd><kwd>ejection fraction</kwd><kwd>end systolic volume</kwd><kwd>end diastolic volume</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lang R., Badano L., Mor-Avi V., Aflalo J., ArmstrongA., Ernande L., Flachskampf F., Foster E., Goldstein S., Kuznetsova T., Lancellotti P., Muraru D., Picard M., Rietzschel E., Rudski L., Spencer K., Tsang W., Voigt J. 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