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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ksma</journal-id><journal-title-group><journal-title xml:lang="ru">Кубанский научный медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Kuban Scientific Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1608-6228</issn><issn pub-type="epub">2541-9544</issn><publisher><publisher-name>Kuban State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25207/1608-6228-2020-27-4-18-26</article-id><article-id custom-type="elpub" pub-id-type="custom">ksma-2282</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>Некоторые аспекты эволюции инфекционной патологии на современном этапе</article-title><trans-title-group xml:lang="en"><trans-title>Selected aspects of infectious disease evolution in the modern world</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малеев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maleyev</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малеев Виктор Васильевич — академик РАН, доктор медицинских наук, профессор, лауреат Государственной премии Российской Федерации в области науки и техники, советник директора</p><p>ул. Новогиреевская, д. 3а, г. Москва, 111123тел.: (495) 974-96-46 </p></bio><bio xml:lang="en"><p>Victor V. Maleyev — Member of the Russian Academy of Sciences, Dr. Sci. (Med.), Prof., Laureate of the State Prize of the Russian Federation in science and technology, an advisor to the Director</p><p>Novogireevskaya str., 3a, Moscow, 111123+ 7 (495) 974-96-46</p></bio><email xlink:type="simple">maleyev@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное бюджетное учреждение науки «Центральный научно-исследовательский институт эпидемиологии Роспотребнадзора»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology of the Federal Service on Customers’ Rights Protection and Human Well-being Surveillance (Rospotrebnadzor)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>13</day><month>08</month><year>2020</year></pub-date><volume>27</volume><issue>4</issue><fpage>18</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малеев В.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Малеев В.В.</copyright-holder><copyright-holder xml:lang="en">Maleyev V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ksma.elpub.ru/jour/article/view/2282">https://ksma.elpub.ru/jour/article/view/2282</self-uri><abstract><p>В статье представлен современный взгляд на эволюцию инфекционного процесса и роль инфекционной патологии в глобальной системе здравоохранения. Инверсия основных составляющих компонент эпидемического процесса приводит к нетипичному течению многих инфекционных болезней и появлению новых особенностей их распространения. Урбанизация, изменение климата на планете, интенсификация агропромышленных производств, высокая миграция населения и другие факторы обуславливают расширение ареала распространения и интродукцию в другие страны и даже континенты многих природно-очаговых инфекций. Высокий уровень инфекционной заболеваемости и смертности на планете определяется как новыми, так и «возвращающимися» инфекциями. В любой момент возможно эпидемическое и даже пандемическое распространение эмерджентных инфекций.</p><p>Чрезвычайно важным в современной инфектологии становится влияние достижений научно-технического прогресса на окружающую ассоциацию микроорганизмов и микробиом человека, а также на безопасность применяемых медицинских технологий.</p><p>Несмотря на достижения лекарственной терапии инфекционных болезней, остро в настоящее время стоит вопрос нарастающего развития антимикробной резистентности и межлекарственного взаимодействия.</p></abstract><trans-abstract xml:lang="en"><p>The article presents current views on the evolution of infectious processes and the role of infectious diseases in global healthcare. The reversion of the main components of epidemic processes leads to an atypical course of many infectious diseases and to the emergence of new transmission pathways. Urbanisation, global climate change, agroindustrial boost, migration waves and other factors provoked a cross-border expansion of many wild focal infections across countries and continents. The high morbidity and mortality of infectious diseases are determined by novel and “resurrecting” infections. The possibility of appearing both epidemic and pandemic outbreaks of emergent infections is as relevant as ever.</p><p>In this context, the impact of modern scientiﬁc achievements on environmental microbiotic associations and human microbiome, as well as safety of medical technologies, is of paramount importance.</p><p>Despite current progress in the drug therapy of infectious diseases, a serious emerging challenge is ampliﬁed antimicrobial resistance and drug interference.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекционная патология</kwd><kwd>эволюция</kwd><kwd>инфекционная заболеваемость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>infectious pathology</kwd><kwd>evolution</kwd><kwd>infectious morbidity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Богадельников И.В., Смирнов Г.И. 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