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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ksma</journal-id><journal-title-group><journal-title xml:lang="ru">Кубанский научный медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Kuban Scientific Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1608-6228</issn><issn pub-type="epub">2541-9544</issn><publisher><publisher-name>Kuban State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25207/1608-6228-2021-28-2-157-169</article-id><article-id custom-type="elpub" pub-id-type="custom">ksma-2469</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF COMMUNICATIONS</subject></subj-group></article-categories><title-group><article-title>Влияние амброзийного пыльцевого дождя в городе Краснодаре на развитие и течение аллергических заболеваний в динамике трех лет: нерандомизированное контролируемое исследование</article-title><trans-title-group xml:lang="en"><trans-title>Ragweed pollen rain impact on allergy rate and severity in Krasnodar: a three-year non-randomised controlled study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клименко</surname><given-names>Я. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimenko</surname><given-names>Ya. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клименко Яна Владимировна — ординатор 1-го года по специальности «Управление и экономика фармации»</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350063</p><p>пр. Кольцевой, д. 15/1, г. Краснодар, 350011</p><p>+7 (952) 844-74-14</p></bio><bio xml:lang="en"><p>Yana V. Klimenko — Clinical Resident (1st year, pharmacy management and economy)</p><p>Mitrofana Sedina str., 4, Krasnodar, 350063</p><p>Koltsevoy travel, 15/1, Krasnodar, 350011</p><p>+7 (952) 844-74-14</p></bio><email xlink:type="simple">yana.klimenk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2528-6781</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мильченко</surname><given-names>Н. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Milchenko</surname><given-names>N. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мильченко Надежда Олеговна — ассистент кафедры биологии с курсом медицинской генетики</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350063</p></bio><bio xml:lang="en"><p>Nadezhda O. Milchenko — Research Assistant, Chair of Biology with course in medical genetics</p><p>Mitrofana Sedina str., 4, Krasnodar, 350063</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0106-0350</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мороз</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Moroz</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мороз Анатолий Николаевич — кандидат биологических наук, доцент кафедры биологии с курсом медицинской генетики</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350063</p></bio><bio xml:lang="en"><p>Anatoly N. Moroz — Cand. Sci. (Biol.), Assoc. Prof., Chair of Biology with course in medical genetics</p><p>Mitrofana Sedina str., 4, Krasnodar, 350063</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8019-9598</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлюченко</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlyuchenko</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павлюченко Иван Иванович — доктор медицинских наук, профессор, заведующий кафедрой биологии с курсом медицинской генетики</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350063</p></bio><bio xml:lang="en"><p>Ivan I. Pavlyuchenko — Dr. Sci. (Med.), Prof., Head of the Chair of Biology with course in medical genetics</p><p>Mitrofana Sedina str., 4, Krasnodar, 350063</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6166-6090</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеенко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеенко Елена Александровна — кандидат медицинских наук, главный врач</p><p>ул. Постовая, д. 18, г. Краснодар, 350063</p></bio><bio xml:lang="en"><p>Elena A. Alekseenko — Cand. Sci. (Med.), Chief Physician</p><p>Postovaya str., 18, 350063, Krasnodar</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения «Городская поликлиника № 26 города Краснодара» Министерства здравоохранения Краснодарского края</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnodar City Outpatient Clinic No. 26</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>24</day><month>03</month><year>2021</year></pub-date><volume>28</volume><issue>2</issue><fpage>157</fpage><lpage>169</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Клименко Я.В., Мильченко Н.О., Мороз А.Н., Павлюченко И.И., Алексеенко Е.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Клименко Я.В., Мильченко Н.О., Мороз А.Н., Павлюченко И.И., Алексеенко Е.А.</copyright-holder><copyright-holder xml:lang="en">Klimenko Y.V., Milchenko N.O., Moroz A.N., Pavlyuchenko I.I., Alekseenko E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ksma.elpub.ru/jour/article/view/2469">https://ksma.elpub.ru/jour/article/view/2469</self-uri><abstract><sec><title>Введение</title><p>Введение. Основным аллергеном в Краснодарском крае, вызывающим поллинозы, является пыльца Ambrosia. Важным прогностическим фактором для специалистов прак­тического здравоохранения и населения, страдающего аллергическими заболеваниями, является информация о сезонных сроках пыления и пиках нарастаниях пыльцы.</p><p>Цель исследования — получение актуальных данных о концентрации пыльцы Ambrosia в атмосфере воздуха города Краснодара в динамике трех лет (2018–2020 гг.), установление зависимости уровня пыления от абиотических и антропогенных факторов среды, влияние показателей пыления на заболеваемость с аллергической составляющей.</p></sec><sec><title>Методы</title><p>Методы. Объект исследования — среднесуточные показатели пыления Ambrosia в атмосферном воздухе города Краснодара. Предмет исследования — обращаемость населения, страдающего аллергическими заболеваниями, за медицинской помощью в зависимости от уровня пыления и содержания пыльцы Амброзии в атмосферном воздухе городской среды.</p></sec><sec><title>Результаты</title><p>Результаты. Максимальный среднесуточный пик пыления Ambrosia наблюдается в августе и составляет: в 2018 году — 663,35 пз/м 3, в 2019 году — 209,89 пз/м 3, в 2020-м — 80,62 пз/м 3. Количество обращений за медицинской помощью населения, страдающего поллинозом, в отдельно взятом городском лечебном учреждении составило: в 2018 г. — 314 человек, в 2019 г. — 335 человек, в 2020 г. — 146 человек. При этом максимальное число обращений пациентов пришлось на сентябрь — октябрь. Исследование зависимости загрязнения окружающей среды на пыление показало следующие результаты: коэффициент корреляции (r) за июль, август, сентябрь и октябрь 2018, 2019 и 2020 гг. в зависимости концентрации пыления Ambrosia от концентрации СО составил 0,356, по NH3 — 0,198, по содержанию пыли — 0,361.</p></sec><sec><title>Заключение</title><p>Заключение. При сопоставлении полученных результатов с данными климатических факторов была выявлена определенная зависимость: максимум пыления выявлен при минимальной влажности (менее 60%), с увеличением влажности концентрация пыльцевых зерен Ambrosia уменьшается, при этом снижение концентрации до минимума является результатом воздействия осадков; увеличение содержания пыльцевых зерен в воздушном спектре происходит при температуре от 20 °C и выше. Значимого влияния степени загрязнения воздуха на концентрацию пыльцы аллергенных растений не установлено. Имеется определенная (средней степени значимости) зависимость между пылением Ambrosia и обращением населения за медицинской помощью.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. The main hay fever agent in Krasnodar Krai is ragweed pollen (Ambrosia gen.). An important alerting guide for medical practitioners and allergic citizens is the seasonal anthetic calendar and pollen peak times.</p></sec><sec><title>Objectives</title><p>Objectives. Obtaining of relevant data on ragweed pollen air contamination rate in Krasnodar in a three-year-dynamics (2018–2020) to estimate the anthetic activity correlation with abiotic and anthropogenic factors and the role of pollen indicators in allergic morbidity.</p></sec><sec><title>Methods</title><p>Methods. We surveyed the daily average ragweed pollen values in Krasnodar air. Allergic medical visits were analysed in terms of the ragweed anthetic activity and pollen air contamination of the city.</p></sec><sec><title>Results</title><p>Results. A maximal daily average ragweed pollen peak occurs in August: 663.35 p.g./m3 in 2018, 209.89 p.g./m3 in 2019, 80.62 p.g./m3 in 2020. Numbers of medical visits for pollinosis per a selected municipal medical facility: 314 in 2018, 335 in 2019 and 146 in 2020, with a peak period in September--October. Analyses of the air pollution impact on ragweed pollen production revealed a correlation between the pollen rate and values of CO (correlation coefficient r-0.356), NH3 (r-0.198) and dust pollution (r-0.361) in July, August, September and October 2018–2020.</p></sec><sec><title>Conclusion</title><p>Conclusion. Analyses of climatic factors uncovered clear patterns: strongest anthesis corresponds to minimal humidity (&lt;60%), the pollen grain content diminishes with lower humidities dropping to minimal with precipitations and increases at temperatures 20 °C and above. No significant dependency was observed between air pollution and the allergic pollen content. Anthesis in ragweed moderately correlates with the rate of medical visits.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>аэропалинология</kwd><kwd>Краснодар</kwd><kwd>aмброзия</kwd><kwd>аллергология</kwd><kwd>иммунология</kwd><kwd>волюметрический пыльцеуловитель VPPS 2000 Lanzoni (Италия)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>aeropalynology</kwd><kwd>Krasnodar</kwd><kwd>ragweed</kwd><kwd>allergology</kwd><kwd>immunology</kwd><kwd>volumetric pollen&#13;
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