ksmaКубанский научный медицинский вестникKuban Scientific Medical Bulletin1608-62282541-9544Kuban State Medical University10.25207/1608-6228-2021-28-3-130-143ksma-2532Research ArticleОБЗОРЫREVIEWПоложительные и отрицательные свойства четырех групп эндодонтических силеров: систематический обзорPositive and negative properties of four endodontic sealant groups: a systematic reviewhttps://orcid.org/0000-0003-1444-1731ЧестныхЕ. В.ChestnyhE. V.

Честных Елена Валерьевна — кандидат медицинских наук, доцент, заведующая кафедрой терапевтической стоматологии федерального государственного бюджетного образовательного учреждения высшего образования «Тверской государственный медицинский университет» Министерства здравоохранения Российской Федерации.

Ул. Советская, д. 4, Тверь, 170100

Elena V. Chestnyh — Cand. Sci. (Med.), Assoc. Prof., Head of the Chair of Therapeutic Dentistry, Tver State Medical University.

Sovetskaya str., 4, Tver, 170100

elenachestnyh@mail.ruhttps://orcid.org/0000-0001-8317-8100ЛаричкинИ. О.LarichkinI. O.

Ларичкин Илья Олегович — ассистент кафедры терапевтической стоматологии федерального государственного бюджетного образовательного учреждения высшего образования «Тверской государственный медицинский университет» Министерства здравоохранения Российской Федерации.

Ул. Советская, д. 4, Тверь, 170100; тел.: +7 (961)018-03-41

Ilia O. Larichkin — Research Assistant, Chair of Therapeutic Dentistry, Tver State Medical University.

Sovetskaya str., 4, Tver, 170100; tel.: +7 (961)018-03-41

don.larichckin2013@yandex.ruhttps://orcid.org/0000-0003-0940-7942ЮсуфоваМ. В.IusufovaM. V.

Юсуфова Мария Владимировна — кандидат медицинских наук, ассистент кафедры терапевтической стоматологии.

Ул. Советская, д. 4, Тверь, 170100

Mariia V. lusufova — Cand. Sci. (Med.), Research Assistant, Chair of Therapeutic Dentistry, Tver State Medical University.

Sovetskaya str., 4, Tver, 170100

usufovamaria@yandex.ruhttps://orcid.org/0000-0003-4005-2430ОрешкинаД. И.OreshkinaD. I.

Орешкина Дарья Игоревна — студентка 4-го курса стоматологического факультета.

Ул. Советская, д. 4, Тверь, 170100

Daria I. Oreshkina — Graduate Student (4th year), Faculty of Dentistry, Tver State Medical University.

Sovetskaya str., 4, Tver, 170100

iraedies3@gmail.comhttps://orcid.org/0000-0002-9464-8769ОрешкинаЕ. И.OreshkinaE. I.

Орешкина Екатерина Игоревна — студентка 4-го курса стоматологического факультета.

Ул. Советская, д. 4, Тверь, 170100

Ekaterina I. Oreshkina — Graduate Student (4th year), Faculty of Dentistry, Tver State Medical University.

Sovetskaya str., 4, Tver, 170100

katyaoresh@yandex.ruhttps://orcid.org/0000-0003-1735-8845МинаковаВ. С.MinakovaV. S.

Минакова Виктория Сергеевна — студентка 4-го курса стоматологического факультета.

Ул. Советская, д. 4, Тверь, 170100

Viktoriia S. Minakova — Graduate Student (4th year), Faculty of Dentistry, Tver State Medical University.

Sovetskaya str., 4, Tver, 170100

minakova.vikulya@mail.ruhttps://orcid.org/0000-0002-3021-7265ПлехановаС. В.PlekhanovaS. V.

Плеханова Софья Валерьевна — студентка 4-го курса стоматологического факультета.

Ул. Советская, д. 4, Тверь, 170100

Sofia V. Plekhanova — Graduate Student (4th year), Faculty of Dentistry, Tver State Medical University.

Sovetskaya str., 4, Tver, 170100

plehanova.sofia@yandex.ruФедеральное государственное бюджетное образовательное учреждение высшего образования Тверской государственный медицинский университет Министерства здравоохранения Российской ФедерацииРоссияTver State Medical UniversityRussian Federation202126062021283130143Copyright © Честных Е.В., Ларичкин И.О., Юсуфова М.В., Орешкина Д.И., Орешкина Е.И., Минакова В.С., Плеханова С.В., 20212021Честных Е.В., Ларичкин И.О., Юсуфова М.В., Орешкина Д.И., Орешкина Е.И., Минакова В.С., Плеханова С.В.Chestnyh E.V., Larichkin I.O., Iusufova M.V., Oreshkina D.I., Oreshkina E.I., Minakova V.S., Plekhanova S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ksma.elpub.ru/jour/article/view/2532Введение

Введение. Выбор силера является для врача-стоматолога важным решением, которое влияет на долгосрочный результат лечения. Знание свойств и характеристик материалов каждой группы имеет решающее значение для выбора наилучшего эндогерметика в каждом конкретном клиническом случае.

Цель обзора - сравнение свойств эндодонтических силеров на основе эпоксидных смол, гидроокиси кальция, цинк-оксид эвгенола и биокерамики.

Методы

Методы. Поиск литературы производился в двух электронных базах: PubMed и Google Scholar и включал в себя статьи по 4 группам силеров (на основе эпоксидных смол, гидроокиси кальция, цинк-оксид эвгенола и биокерамики), опубликованные с 2014 по 2021 год, а также отдельные значимые публикации за период 2002-2013 гг. В обзор были включено 73 статьи независимо от дизайна исследования и языка публикации. Методы исследования, использованные в процессе анализа: контент-анализ и описательно-аналитический. Метаанализ не проводился в связи с высокой неоднородностью исследований.

Результаты

Результаты. В настоящее время на рынке стоматологических материалов представлено много силеров различных групп. Наиболее широкое распространение получили эндодонтические герметики на основе эпоксидных смол, цинк-оксид эвгенола, гидроокиси кальция и биокерамики. Обзор показывает отсутствие идеального материала для пломбирования корневых каналов.

Заключение

Заключение. Многочисленные исследования показывают преимущества и недостатки каждой группы эндодонтических силеров при сравнении по разным критериям. В зависимости от клинической ситуации врач может использовать то или иное свойство данных материалов, выбирая необходимый эндогерметик.

Background

Background. The choice of sealant is an important dentist’s decision with a long-term influence on treatment. Knowledge of the properties and characters of each material is key to the optimal endosealer selection on individual basis.

Objectives

Objectives. A comparison of endodontic sealants based on epoxy resins, calcium hydroxide, zinc oxide eugenol and bioceramics.

Methods

Methods. Publications were mined in the PubMed and Google Scholar electronic databases to cover the four sealer groups (epoxy, calcium hydroxide, zinc oxide eugenol and bioceramics) over years 2014-2021, including selected relevant sources within 2002-2013; 73 articles were considered for review, regardless of the study design or language. Content and descriptive analyses were used as research tools. Meta-analysis was not used due to a high evidence heterogeneity.

Results

Results. The dental market currently offers a variety of sealant groups. Endodontic sealants based on epoxy resins, zinc oxide eugenol, calcium hydroxide and bioceramics are the most common. The review identifies no ideal material for the root canal filling.

Conclusion

Conclusion. Manifold studies demonstrate the pros and cons in each endodontic sealant group with respect to variant criteria. Depending on clinical situation, the practitioner can opt for the material property to identify the endosealer.

эндодонтический силерэпоксидная смолагидроокись кальцияцинк-оксид эвгенолбиокерамикаendodontic sealantepoxy resincalcium hydroxidezinc oxide eugenolbioceramicsReferencesHolland R., Gomes J.E. Filho, Cintra L.T.A., Queiroz LO.A., Estrela C. Factors affecting the periapical healing process of endodontically treated teeth. J. Appl. Oral. Sci. 2017; 25(5): 465-476. DOI: 10.1590/1678-7757-2016-0464Holland R., Gomes J.E. Filho, Cintra L.T.A., Queiroz LO.A., Estrela C. Factors affecting the periapical healing process of endodontically treated teeth. J. Appl. Oral. Sci. 2017; 25(5): 465-476. DOI: 10.1590/1678-7757-2016-0464Komabayashi T., Colmenar D., Cvach N., Bhat A., Primus C., Imai Y. Comprehensive review of current endodontic sealers. Dent. Mater. J. 2020; 39(5): 703720. DOI: 10.4012/dmj.2019-288Komabayashi T., Colmenar D., Cvach N., Bhat A., Primus C., Imai Y. Comprehensive review of current endodontic sealers. Dent. Mater. J. 2020; 39(5): 703720. DOI: 10.4012/dmj.2019-288Reszka P., Nowicka A., Lipski M., Dura W., Drozdzik A., Wozniak K. A comparative chemical study of calcium silicate-containing and epoxy resin-based root canal sealers. Biomed. Res. Int. 2016; 2016: 9808432. DOI: 10.1155/2016/9808432Reszka P., Nowicka A., Lipski M., Dura W., Drozdzik A., Wozniak K. A comparative chemical study of calcium silicate-containing and epoxy resin-based root canal sealers. Biomed. Res. Int. 2016; 2016: 9808432. DOI: 10.1155/2016/9808432Mendes A.T., Silva P.B.D., So B.B., Hashizume L.N., Vivan R.R., Rosa R.A.D., Duarte M.A.H., So M.V.R. Evaluation of physicochemical properties of new calcium silicate-based sealer. Braz. Dent. J. 2018; 29(6): 536-540. DOI: 10.1590/0103-6440201802088Mendes A.T., Silva P.B.D., So B.B., Hashizume L.N., Vivan R.R., Rosa R.A.D., Duarte M.A.H., So M.V.R. Evaluation of physicochemical properties of new calcium silicate-based sealer. Braz. Dent. J. 2018; 29(6): 536-540. DOI: 10.1590/0103-6440201802088Kuga M.C., Duarte M.A., Sant'anna-Junior A., Keine K.C., Faria G., Dantas A.A., Guiotti F.A. Effects of calcium hydroxide addition on the physical and chemical properties of a calcium silicate-based sealer. J. Appl. Oral. Sci. 2014; 22(3): 180-184. DOI: 10.1590/1678-775720130032Kuga M.C., Duarte M.A., Sant'anna-Junior A., Keine K.C., Faria G., Dantas A.A., Guiotti F.A. Effects of calcium hydroxide addition on the physical and chemical properties of a calcium silicate-based sealer. J. Appl. Oral. Sci. 2014; 22(3): 180-184. DOI: 10.1590/1678-775720130032Kaur A., Shah N., Logani A., Mishra N. Biotoxicity of commonly used root canal sealers: A metaanalysis. J. Conserv. Dent. 2015; 18(2): 83-88. DOI: 10.4103/0972-0707.153054Kaur A., Shah N., Logani A., Mishra N. Biotoxicity of commonly used root canal sealers: A metaanalysis. J. Conserv. Dent. 2015; 18(2): 83-88. DOI: 10.4103/0972-0707.153054Jitaru S., Hodisan I., Timis L., Lucian A., Bud M. The use of bioceramics in endodontics — literature review. Clujul. Med. 2016; 89(4): 470-473. DOI: 10.15386/cjmed-612Jitaru S., Hodisan I., Timis L., Lucian A., Bud M. The use of bioceramics in endodontics — literature review. Clujul. Med. 2016; 89(4): 470-473. DOI: 10.15386/cjmed-612Fonseca D.A., Paula A.B., Marto C.M., Coelho A., Paulo S., Martinho J.P., Carrilho E., Ferreira M.M. Biocompatibility of root canal sealers: a systematic review of in vitro and in vivo studies. Materials (Basel). 2019; 12(24): 4113. DOI: 10.3390/ma12244113Fonseca D.A., Paula A.B., Marto C.M., Coelho A., Paulo S., Martinho J.P., Carrilho E., Ferreira M.M. Biocompatibility of root canal sealers: a systematic review of in vitro and in vivo studies. Materials (Basel). 2019; 12(24): 4113. DOI: 10.3390/ma12244113Simsek N., Akinci L., Gecor O., Alan H., Ahmetoglu F., Taslidere E. Biocompatibility of a new epoxy resin-based root canal sealer in subcutaneous tissue of rat. Eur. J. Dent. 2015; 9(1): 31-35. DOI: 10.4103/1305-7456.149635Simsek N., Akinci L., Gecor O., Alan H., Ahmetoglu F., Taslidere E. Biocompatibility of a new epoxy resin-based root canal sealer in subcutaneous tissue of rat. Eur. J. Dent. 2015; 9(1): 31-35. DOI: 10.4103/1305-7456.149635Troiano G., Perrone D., Dioguardi M., Buonavoglia A., Ardito F., Lo Muzio L. In vitro evaluation of the cytotoxic activity of three epoxy resin-based endodontic sealers. Dent. Mater. J. 2018; 37(3): 374-378. DOI: 10.4012/dmj.2017-148Troiano G., Perrone D., Dioguardi M., Buonavoglia A., Ardito F., Lo Muzio L. In vitro evaluation of the cytotoxic activity of three epoxy resin-based endodontic sealers. Dent. Mater. J. 2018; 37(3): 374-378. DOI: 10.4012/dmj.2017-148Oh H., Kim E., Lee S., Park S., Chen D., Shin S.J., Kim E., Kim S. Comparison of biocompatibility of calcium silicate-based sealers and epoxy resin-based sealer on human periodontal ligament stem cells. Materials (Basel). 2020; 13(22): 5242. DOI: 10.3390/ma13225242Oh H., Kim E., Lee S., Park S., Chen D., Shin S.J., Kim E., Kim S. Comparison of biocompatibility of calcium silicate-based sealers and epoxy resin-based sealer on human periodontal ligament stem cells. Materials (Basel). 2020; 13(22): 5242. DOI: 10.3390/ma13225242Cintra L.T., Ribeiro T.A., Gomes-Filho J.E., Berna-be P.F., Watanabe S., Facundo A.C., Samuel R.O., Dezan-JuniorE. Biocompatibilityand biomineralization assessment of a new root canal sealer and root-end filling material. Dent. Traumatol. 2013; 29(2): 145150. DOI: 10.1111/j.1600-9657.2012.01142.xCintra L.T., Ribeiro T.A., Gomes-Filho J.E., Berna-be P.F., Watanabe S., Facundo A.C., Samuel R.O., Dezan-JuniorE. Biocompatibilityand biomineralization assessment of a new root canal sealer and root-end filling material. Dent. Traumatol. 2013; 29(2): 145150. DOI: 10.1111/j.1600-9657.2012.01142.xBenetti F., de Azevedo Queiroz I.O., Oliveira P.H.C., Conti L.C., Azuma M.M., Oliveira S.H.P., Cintra L.T.A. Cytotoxicity and biocompatibility of a new bioceramic endodontic sealer containing calcium hydroxide. Braz. Oral. Res. 2019; 33: e042. DOI: 10.1590/1807-3107bor-2019.vol33.0042Benetti F., de Azevedo Queiroz I.O., Oliveira P.H.C., Conti L.C., Azuma M.M., Oliveira S.H.P., Cintra L.T.A. Cytotoxicity and biocompatibility of a new bioceramic endodontic sealer containing calcium hydroxide. Braz. Oral. Res. 2019; 33: e042. DOI: 10.1590/1807-3107bor-2019.vol33.0042Leonardo M.R., Hernandez M.E., Silva L.A., Tanomaru-Filho M. Effect of a calcium hydroxide-based root canal dressing on periapical repair in dogs: a histological study. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod. 2006; 102(5): 680685. DOI: 10.1016/j.tripleo.2006.03.021Leonardo M.R., Hernandez M.E., Silva L.A., Tanomaru-Filho M. Effect of a calcium hydroxide-based root canal dressing on periapical repair in dogs: a histological study. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod. 2006; 102(5): 680685. DOI: 10.1016/j.tripleo.2006.03.021Lee J.H., Lee H.H., Kim H.W., Yu J.W., Kim K.N., Kim K.M. Immunomodulatory/anti-inflammatory effect of ZOE-based dental materials. Dent. Mater. 2017; 33(1): e1-e12. DOI: 10.1016/j.dental.2016.09.012Lee J.H., Lee H.H., Kim H.W., Yu J.W., Kim K.N., Kim K.M. Immunomodulatory/anti-inflammatory effect of ZOE-based dental materials. Dent. Mater. 2017; 33(1): e1-e12. DOI: 10.1016/j.dental.2016.09.012Jung S., Libricht V., Sielker S., Hanisch M.R., Schafer E., Dammaschke T. Evaluation of the biocompatibility of root canal sealers on human periodontal ligament cells ex vivo. Odontology. 2019; 107(1): 54-63. DOI: 10.1007/s10266-018-0380-3Jung S., Libricht V., Sielker S., Hanisch M.R., Schafer E., Dammaschke T. Evaluation of the biocompatibility of root canal sealers on human periodontal ligament cells ex vivo. Odontology. 2019; 107(1): 54-63. DOI: 10.1007/s10266-018-0380-3Jung S., Sielker S., Hanisch M.R., Libricht V., Schafer E., Dammaschke T. Cytotoxic effects of four different root canal sealers on human osteoblasts. PLoS. One. 2018; 13(3): e0194467. DOI: 10.1371/journal.pone.0194467Jung S., Sielker S., Hanisch M.R., Libricht V., Schafer E., Dammaschke T. Cytotoxic effects of four different root canal sealers on human osteoblasts. PLoS. One. 2018; 13(3): e0194467. DOI: 10.1371/journal.pone.0194467Santos J.M., Pereira S., Sequeira D.B., Messias A.L., Martins J.B., Cunha H., Palma PJ., Santos A.C. Biocompatibility of a bioceramic silicone-based sealer in subcutaneous tissue. J. Oral. Sci. 2019; 61(1): 171177. DOI: 10.2334/josnusd.18-0145Santos J.M., Pereira S., Sequeira D.B., Messias A.L., Martins J.B., Cunha H., Palma PJ., Santos A.C. Biocompatibility of a bioceramic silicone-based sealer in subcutaneous tissue. J. Oral. Sci. 2019; 61(1): 171177. DOI: 10.2334/josnusd.18-0145Giacomino C.M.,Wealleans J.A., Kuhn N., Diogenes A. Comparative biocompatibility and osteogenic potential of two bioceramic sealers. J. Endod. 2019; 45(1): 5156. DOI: 10.1016/j.joen.2018.08.007Giacomino C.M.,Wealleans J.A., Kuhn N., Diogenes A. Comparative biocompatibility and osteogenic potential of two bioceramic sealers. J. Endod. 2019; 45(1): 5156. DOI: 10.1016/j.joen.2018.08.007Alves Silva E.C., Tanomaru-Filho M., da Silva G.F., Delfino M.M., Cerri P.S., Guerreiro-Tanomaru J.M. Biocompatibility and bioactive potential of new calcium silicate-based endodontic sealers: Bio-C Sealer and Sealer Plus BC. J. Endod. 2020; 46(10): 1470-1477. DOI: 10.1016/j.joen.2020.07.011Alves Silva E.C., Tanomaru-Filho M., da Silva G.F., Delfino M.M., Cerri P.S., Guerreiro-Tanomaru J.M. Biocompatibility and bioactive potential of new calcium silicate-based endodontic sealers: Bio-C Sealer and Sealer Plus BC. J. Endod. 2020; 46(10): 1470-1477. DOI: 10.1016/j.joen.2020.07.011Al-Haddad A., Che Ab Aziz Z.A. Bioceramic-based root canal sealers: a review. Int. J. Biomater. 2016; 2016: 9753210. DOI: 10.1155/2016/9753210Al-Haddad A., Che Ab Aziz Z.A. Bioceramic-based root canal sealers: a review. Int. J. Biomater. 2016; 2016: 9753210. DOI: 10.1155/2016/9753210Cintra L.T.A., Benetti F., de Azevedo Queiroz I.O., Ferreira L.L, Massunari L., Bueno C.R.E., de Olive i -ra S.H.P., Gomes-Filho J.E. Evaluation of the cytotoxicity and biocompatibility of new resin epoxy-based endodontic sealer containing calcium hydroxide. J. Endod. 2017; 43(12): 2088-2092. DOI: 10.1016/j.joen.2017.07.016Cintra L.T.A., Benetti F., de Azevedo Queiroz I.O., Ferreira L.L, Massunari L., Bueno C.R.E., de Olive i -ra S.H.P., Gomes-Filho J.E. Evaluation of the cytotoxicity and biocompatibility of new resin epoxy-based endodontic sealer containing calcium hydroxide. J. Endod. 2017; 43(12): 2088-2092. DOI: 10.1016/j.joen.2017.07.016Bueno C.R., Valentim D., Marques V.A., Gomes-Filho J.E., Cintra L.T., Jacinto R.C., Dezan-Junior E. Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers. Braz. Oral. Res. 2016; 30(1): S1806-83242016000100267. DOI: 10.1590/1807-3107BOR-2016.vol30.0081Bueno C.R., Valentim D., Marques V.A., Gomes-Filho J.E., Cintra L.T., Jacinto R.C., Dezan-Junior E. Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers. Braz. Oral. Res. 2016; 30(1): S1806-83242016000100267. DOI: 10.1590/1807-3107BOR-2016.vol30.0081Bukhari S., Karabucak B. The antimicrobial effect of bioceramic sealer on an 8-week matured enterococcus faecalis biofilm attached to root canal dentinal surface. J. Endod. 2019; 45(8): 1047-1052. DOI: 10.1016/j.joen.2019.04.004.Bukhari S., Karabucak B. The antimicrobial effect of bioceramic sealer on an 8-week matured enterococcus faecalis biofilm attached to root canal dentinal surface. J. Endod. 2019; 45(8): 1047-1052. DOI: 10.1016/j.joen.2019.04.004.Silva E.J., Hecksher F., Vieira V.T., Vivan R.R., Duarte M.A., Brasil S.C., Antunes H.S. Cytotoxicity, antibacterial and physicochemical properties of a new epoxy resin-based endodontic sealer containing calcium hydroxide. J. Clin. Exp. Dent. 2020; 12(6): e533-e539. DOI: 10.4317/jced.56534Silva E.J., Hecksher F., Vieira V.T., Vivan R.R., Duarte M.A., Brasil S.C., Antunes H.S. Cytotoxicity, antibacterial and physicochemical properties of a new epoxy resin-based endodontic sealer containing calcium hydroxide. J. Clin. Exp. Dent. 2020; 12(6): e533-e539. DOI: 10.4317/jced.56534Louwakul P, Saelo A., Khemaleelakul S. Efficacy of calcium oxide and calcium hydroxide nanoparticles on the elimination of Enterococcus faecalis in human root dentin. Clin. Oral. Investig. 2017; 21(3): 865-871. DOI: 10.1007/s00784-016-1836-xLouwakul P, Saelo A., Khemaleelakul S. Efficacy of calcium oxide and calcium hydroxide nanoparticles on the elimination of Enterococcus faecalis in human root dentin. Clin. Oral. Investig. 2017; 21(3): 865-871. DOI: 10.1007/s00784-016-1836-xMeto A., Colombari B., Sala A., Pericolini E., Meto A., Peppoloni S., Blasi E. Antimicrobial and antibiofilm efficacy of a copper/calcium hydroxide-based endodontic paste against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. Dent. Mater. J. 2019; 38(4): 591-603. DOI: 10.4012/dmj.2018-252Meto A., Colombari B., Sala A., Pericolini E., Meto A., Peppoloni S., Blasi E. Antimicrobial and antibiofilm efficacy of a copper/calcium hydroxide-based endodontic paste against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. Dent. Mater. J. 2019; 38(4): 591-603. DOI: 10.4012/dmj.2018-252Barbosa-Ribeiro M., Arruda-Vasconcelos R., de-Jesus-Soares A., Zaia A.A., Ferraz C.C.R., de Almeida J.F.A., Gomes B.P.F.A. Effectiveness of calcium hydroxide-based intracanal medication on infectious/inflammatory contents in teeth with posttreatment apical periodontitis. Clin. Oral. Investig. 2019; 23(6): 2759-2766. DOI: 10.1007/s00784-018-2719-0Barbosa-Ribeiro M., Arruda-Vasconcelos R., de-Jesus-Soares A., Zaia A.A., Ferraz C.C.R., de Almeida J.F.A., Gomes B.P.F.A. Effectiveness of calcium hydroxide-based intracanal medication on infectious/inflammatory contents in teeth with posttreatment apical periodontitis. Clin. Oral. Investig. 2019; 23(6): 2759-2766. DOI: 10.1007/s00784-018-2719-0Rezende G.C., Massunari L., Queiroz I.O., Gomes Filho J.E., Jacinto R.C., Lodi C.S., Dezan Junior E. Antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against E. faecalis biofilm. Braz. Oral. Res. 2016; 30: S1806-83242016000100228. DOI: 10.1590/1807-3107BOR-2016.vol30.0038Rezende G.C., Massunari L., Queiroz I.O., Gomes Filho J.E., Jacinto R.C., Lodi C.S., Dezan Junior E. Antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against E. faecalis biofilm. Braz. Oral. Res. 2016; 30: S1806-83242016000100228. DOI: 10.1590/1807-3107BOR-2016.vol30.0038Kim T., Kim M.A., Hwang Y.C., Rosa V., Del Fab-bro M., Min K.S. Effect of a calcium hydroxide-based intracanal medicament containing N-2-methyl pyrrolidone as a vehicle against Enterococcus faecalis biofilm. J. Appl. Oral. Sci. 2020; 28: e20190516. DOI: 10.1590/1678-7757-2019-0516Kim T., Kim M.A., Hwang Y.C., Rosa V., Del Fab-bro M., Min K.S. Effect of a calcium hydroxide-based intracanal medicament containing N-2-methyl pyrrolidone as a vehicle against Enterococcus faecalis biofilm. J. Appl. Oral. Sci. 2020; 28: e20190516. DOI: 10.1590/1678-7757-2019-0516Buurma H.A., Buurma B.J. The effect of smear layer on bacterial penetration through roots obturated using zinc oxide eugenol-based sealer. BMC Oral. Health. 2020; 20(1): 88. DOI: 10.1186/s12903-020-01069-8Buurma H.A., Buurma B.J. The effect of smear layer on bacterial penetration through roots obturated using zinc oxide eugenol-based sealer. BMC Oral. Health. 2020; 20(1): 88. DOI: 10.1186/s12903-020-01069-8Dalmia S., Gaikwad A., Samuel R., Aher G., Gulve M., Kolhe S. Antimicrobial efficacy of different endodontic sealers against enterococcus faecalis: an in vitro study. J. Int. Soc. Prev. Community. Dent. 2018; 8(2): 104-109. DOI: 10.4103/jispcd.JISPCD_29_18Dalmia S., Gaikwad A., Samuel R., Aher G., Gulve M., Kolhe S. Antimicrobial efficacy of different endodontic sealers against enterococcus faecalis: an in vitro study. J. Int. Soc. Prev. Community. Dent. 2018; 8(2): 104-109. DOI: 10.4103/jispcd.JISPCD_29_18Anumula L., Kumar S., Kumar V.S., Sekhar C., Krishna M., Pathapati R.M., Venkata Sarath P., Vadaganadam Y., Manne R.K., Mudlapudi S. An Assessment of Antibacterial Activity of Four Endodontic Sealers on Enterococcus faecalis by a Direct Contact Test: An In Vitro Study. ISRN Dent. 2012; 2012: 989781. DOI: 10.5402/2012/989781Anumula L., Kumar S., Kumar V.S., Sekhar C., Krishna M., Pathapati R.M., Venkata Sarath P., Vadaganadam Y., Manne R.K., Mudlapudi S. An Assessment of Antibacterial Activity of Four Endodontic Sealers on Enterococcus faecalis by a Direct Contact Test: An In Vitro Study. ISRN Dent. 2012; 2012: 989781. DOI: 10.5402/2012/989781Binoy D., Sajjan G.S., Peddireddi S., Kumar M.S., Bhavana V., Raju S.R. A comparitive evaluation of sealing ability, ph and rheological properties of zinc oxide eugenol sealer combined with different antibiotics: an in vitro study. J. Clin. Diagn. Res. 2014; 8(11): ZC05-8. DOI: 10.7860/JCDR/2014/8398.5095Binoy D., Sajjan G.S., Peddireddi S., Kumar M.S., Bhavana V., Raju S.R. A comparitive evaluation of sealing ability, ph and rheological properties of zinc oxide eugenol sealer combined with different antibiotics: an in vitro study. J. Clin. Diagn. Res. 2014; 8(11): ZC05-8. DOI: 10.7860/JCDR/2014/8398.5095Candeiro G.T.M., Moura-Netto C., D'Almeida-Couto R.S., Azambuja-Junior N., Marques M.M., Cai S., Gavini G. Cytotoxicity, genotoxicity and antibacterial effectiveness of a bioceramic endodontic sealer. Int. Endod. J. 2016; 49(9): 858-864. DOI: 10.1111/iej.12523Candeiro G.T.M., Moura-Netto C., D'Almeida-Couto R.S., Azambuja-Junior N., Marques M.M., Cai S., Gavini G. Cytotoxicity, genotoxicity and antibacterial effectiveness of a bioceramic endodontic sealer. Int. Endod. J. 2016; 49(9): 858-864. DOI: 10.1111/iej.12523Poggio C., Dagna A., Ceci M., Meravini M.V., Colombo M., Pietrocola G. Solubility and pH of bioceramic root canal sealers: A comparative study. J. Clin. Exp. Dent. 2017; 9(10): e1189-e1194. DOI: 10.4317/jced.54040Poggio C., Dagna A., Ceci M., Meravini M.V., Colombo M., Pietrocola G. Solubility and pH of bioceramic root canal sealers: A comparative study. J. Clin. Exp. Dent. 2017; 9(10): e1189-e1194. DOI: 10.4317/jced.54040Bose R., Ioannidis K., Foschi F., Bakhsh A., Kelly R.D., Deb S., Mannocci F., Niazi S.A. Antimicrobial Effectiveness of Calcium Silicate Sealers against a Nutrient-Stressed Multispecies Biofilm. J. Clin. Med. 2020; 9(9): 2722. DOI: 10.3390/jcm9092722Bose R., Ioannidis K., Foschi F., Bakhsh A., Kelly R.D., Deb S., Mannocci F., Niazi S.A. Antimicrobial Effectiveness of Calcium Silicate Sealers against a Nutrient-Stressed Multispecies Biofilm. J. Clin. Med. 2020; 9(9): 2722. DOI: 10.3390/jcm9092722Wang Y., Liu S., Dong Y. In vitro study of dentinal tubule penetration and filling quality of bioceramic sealer. PLoS One. 2018; 13(2): e0192248. DOI: 10.1371/journal.pone.0192248Wang Y., Liu S., Dong Y. In vitro study of dentinal tubule penetration and filling quality of bioceramic sealer. PLoS One. 2018; 13(2): e0192248. DOI: 10.1371/journal.pone.0192248Raghavendra S.S., Jadhav G.R., Gathani K.M., Kotadia P. Bioceramics in endodontics — a review. J. Istanb. Univ. Fac Dent. 2017; 51(3 Suppl 1): S128-S137. DOI: 10.17096/jiufd.63659Raghavendra S.S., Jadhav G.R., Gathani K.M., Kotadia P. Bioceramics in endodontics — a review. J. Istanb. Univ. Fac Dent. 2017; 51(3 Suppl 1): S128-S137. DOI: 10.17096/jiufd.63659Mendes A.T., Silva P.B.D., So B.B., Hashizume L.N., Vivan R.R., Rosa R.A.D., Duarte M.A.H., So M.V.R. Evaluation of Physicochemical Properties of New Calcium Silicate-Based Sealer. Braz. Dent. J. 2018; 29(6): 536-540. DOI: 10.1590/0103-6440201802088Mendes A.T., Silva P.B.D., So B.B., Hashizume L.N., Vivan R.R., Rosa R.A.D., Duarte M.A.H., So M.V.R. Evaluation of Physicochemical Properties of New Calcium Silicate-Based Sealer. Braz. Dent. J. 2018; 29(6): 536-540. DOI: 10.1590/0103-6440201802088Guneser M.B., Arslan D., Dincer A.N., Er G. Effect of sodium hypochlorite irrigation with or without surfactants on the bond strength of an epoxy-based sealer to dentin. Clin. Oral. Investig. 2017; 21(4): 1259-1265. DOI: 10.1007/s00784-016-1885-1Guneser M.B., Arslan D., Dincer A.N., Er G. Effect of sodium hypochlorite irrigation with or without surfactants on the bond strength of an epoxy-based sealer to dentin. Clin. Oral. Investig. 2017; 21(4): 1259-1265. DOI: 10.1007/s00784-016-1885-1Neelakantan P, Sharma S., Shemesh H., Wesse-link PR. Influence of irrigation sequence on the adhesion of root canal sealers to dentin: a fourier transform infrared spectroscopy and push-out bond strength analysis. J. Endod. 2015; 41(7): 1108-1111. DOI: 10.1016/j.joen.2015.02.001Neelakantan P, Sharma S., Shemesh H., Wesse-link PR. Influence of irrigation sequence on the adhesion of root canal sealers to dentin: a fourier transform infrared spectroscopy and push-out bond strength analysis. J. Endod. 2015; 41(7): 1108-1111. DOI: 10.1016/j.joen.2015.02.001Patni P.M., Chandak M., Jain P, Patni M.J., Jain S., Mishra P, Jain V. Stereomicroscopic evaluation of sealing ability of four different root canal sealers- an invitro study. J. Clin. Diagn. Res. 2016; 10(8): ZC37-ZC39. DOI: 10.7860/JCDR/2016/19477.8246Patni P.M., Chandak M., Jain P, Patni M.J., Jain S., Mishra P, Jain V. Stereomicroscopic evaluation of sealing ability of four different root canal sealers- an invitro study. J. Clin. Diagn. Res. 2016; 10(8): ZC37-ZC39. DOI: 10.7860/JCDR/2016/19477.8246Lee K.W., Williams M.C., Camps J.J., Pashley D.H. Adhesion of endodontic sealers to dentin and guttapercha. J. Endod. 2002; 28(10): 684-688. DOI: 10.1097/00004770-200210000-00002Lee K.W., Williams M.C., Camps J.J., Pashley D.H. Adhesion of endodontic sealers to dentin and guttapercha. J. Endod. 2002; 28(10): 684-688. DOI: 10.1097/00004770-200210000-00002Alsubait S., Alsaad N., Alahmari S., Alfaraj F., Alfawaz H., Alqedairi A. The effect of intracanal medicaments used in Endodontics on the dislocation resistance of two calcium silicate-based filling materials. BMC Oral. Health. 2020; 20(1): 57. DOI: 10.1186/s12903-020-1044-6Alsubait S., Alsaad N., Alahmari S., Alfaraj F., Alfawaz H., Alqedairi A. The effect of intracanal medicaments used in Endodontics on the dislocation resistance of two calcium silicate-based filling materials. BMC Oral. Health. 2020; 20(1): 57. DOI: 10.1186/s12903-020-1044-6Moinzadeh A.T., De Moor R.J.G., De Bruyne M.A.A. Influence of a calcium hydroxide-based intracanal dressing on the quality of the root canal filling assessed by capillary flow porometry. Clin. Oral. Investig. 2018; 22(4): 1733-1739. DOI: 10.1007/s00784-017-2267-zMoinzadeh A.T., De Moor R.J.G., De Bruyne M.A.A. Influence of a calcium hydroxide-based intracanal dressing on the quality of the root canal filling assessed by capillary flow porometry. Clin. Oral. Investig. 2018; 22(4): 1733-1739. DOI: 10.1007/s00784-017-2267-zHawkins J.J., Torabinejad M., Li Y., Retamozo B. Effect of three calcium hydroxide formulations on fracture resistance of dentin over time. Dent. Traumatol. 2015; 31(5): 380-384. DOI: 10.1111/edt.12175Hawkins J.J., Torabinejad M., Li Y., Retamozo B. Effect of three calcium hydroxide formulations on fracture resistance of dentin over time. Dent. Traumatol. 2015; 31(5): 380-384. DOI: 10.1111/edt.12175Javidi M., Zarei M., Naghavi N., Mortazavi M., Nejat A.H. Zinc oxide nano-particles as sealer in endodontics and its sealing ability. Contemp. Clin. Dent. 2014; 5(1): 2024. DOI: 10.4103/0976-237X.128656Javidi M., Zarei M., Naghavi N., Mortazavi M., Nejat A.H. Zinc oxide nano-particles as sealer in endodontics and its sealing ability. Contemp. Clin. Dent. 2014; 5(1): 2024. DOI: 10.4103/0976-237X.128656Ha J.H., Kim H.C., Kim Y.K., Kwon T.Y. An evaluation of wetting and adhesion of three bioceramic root canal sealers to intraradicular human dentin. Materials (Basel). 2018; 11(8): 1286. DOI: 10.3390/ma11081286Ha J.H., Kim H.C., Kim Y.K., Kwon T.Y. An evaluation of wetting and adhesion of three bioceramic root canal sealers to intraradicular human dentin. Materials (Basel). 2018; 11(8): 1286. DOI: 10.3390/ma11081286Modh H., Sequeira V., A. Belur, Arun N., Dhas S., Fernandes G. Newer Trends in Endodontic Treatment: A Review. IOSR Journal of Dental and Medical Sciences. 2018; 17(01): 14-16. DOI: 10.9790/0853-1701101416Modh H., Sequeira V., A. Belur, Arun N., Dhas S., Fernandes G. Newer Trends in Endodontic Treatment: A Review. IOSR Journal of Dental and Medical Sciences. 2018; 17(01): 14-16. DOI: 10.9790/0853-1701101416Asawaworarit W., Pinyosopon T., Kijsamanmith K. Comparison of apical sealing ability of bioceramic sealer and epoxy resin-based sealer using the fluid filtration technique and scanning electron microscopy. J. Dent. Sci. 2020; 15(2): 186-192. DOI: 10.1016/j.jds.2019.09.010Asawaworarit W., Pinyosopon T., Kijsamanmith K. Comparison of apical sealing ability of bioceramic sealer and epoxy resin-based sealer using the fluid filtration technique and scanning electron microscopy. J. Dent. Sci. 2020; 15(2): 186-192. DOI: 10.1016/j.jds.2019.09.010Arikatla S.K., Chalasani U., Mandava J., Yelise-la R.K. Interfacial adaptation and penetration depth of bioceramic endodontic sealers. J. Conserv. Dent. 2018; 21(4): 373-377. DOI: 10.4103/JCD.JCD_64_18Arikatla S.K., Chalasani U., Mandava J., Yelise-la R.K. Interfacial adaptation and penetration depth of bioceramic endodontic sealers. J. Conserv. Dent. 2018; 21(4): 373-377. DOI: 10.4103/JCD.JCD_64_18Furtado T.C., de Bem I.A., Machado L.S., Pereira J.R., So M.V.R., da Rosa R.A. Intratubular penetration of endodontic sealers depends on the fluorophore used for CLSM assessment. Microsc. Res. Tech. 2021; 84(2): 305-312. DOI: 10.1002/jemt.23589Furtado T.C., de Bem I.A., Machado L.S., Pereira J.R., So M.V.R., da Rosa R.A. Intratubular penetration of endodontic sealers depends on the fluorophore used for CLSM assessment. Microsc. Res. Tech. 2021; 84(2): 305-312. DOI: 10.1002/jemt.23589Candeiro G.T.M., Lavor A.B., Lima I.T.F., Vasconce-los B.C., Gomes N.V., Iglecias E.F., Gavini G. Penetration of bioceramic and epoxy-resin endodontic cements into lateral canals. Braz. Oral. Res. 2019; 33: e049. DOI: 10.1590/1807-3107bor-2019.vol33.0049Candeiro G.T.M., Lavor A.B., Lima I.T.F., Vasconce-los B.C., Gomes N.V., Iglecias E.F., Gavini G. Penetration of bioceramic and epoxy-resin endodontic cements into lateral canals. Braz. Oral. Res. 2019; 33: e049. DOI: 10.1590/1807-3107bor-2019.vol33.0049Coronas V.S., Villa N., Nascimento A.L.D., Duarte P.H.M., Rosa R.A.D., So M.V.R. Dentinal Tubule Penetration of a Calcium Silicate-Based Root Canal Sealer Using a Specific Calcium Fluorophore. Braz. Dent. J. 2020; 31(2): 109-115. DOI: 10.1590/0103-6440202002829Coronas V.S., Villa N., Nascimento A.L.D., Duarte P.H.M., Rosa R.A.D., So M.V.R. Dentinal Tubule Penetration of a Calcium Silicate-Based Root Canal Sealer Using a Specific Calcium Fluorophore. Braz. Dent. J. 2020; 31(2): 109-115. DOI: 10.1590/0103-6440202002829Roizenblit R.N., Soares F.O., Lopes R.T., Dos Santos B.C., Gusman H. Root canal filling quality of mandibular molars with EndoSequence BC and AH Plus sealers: A micro-CT study. Aust. Endod. J. 2020; 46(1): 82-87. DOI: 10.1111/aej.12373Roizenblit R.N., Soares F.O., Lopes R.T., Dos Santos B.C., Gusman H. Root canal filling quality of mandibular molars with EndoSequence BC and AH Plus sealers: A micro-CT study. Aust. Endod. J. 2020; 46(1): 82-87. DOI: 10.1111/aej.12373Marashdeh M.Q., Friedman S., Levesque C., Finer Y. Esterases affect the physical properties of materials used to seal the endodontic space. Dent. Mater. 2019; 35(8): 1065-1072. DOI: 10.1016/j.dental.2019.04.011Marashdeh M.Q., Friedman S., Levesque C., Finer Y. Esterases affect the physical properties of materials used to seal the endodontic space. Dent. Mater. 2019; 35(8): 1065-1072. DOI: 10.1016/j.dental.2019.04.011Zhou H.M., Shen Y., Zheng W., Li L., Zheng Y.F., Haapasalo M. Physical properties of 5 root canal sealers. J. Endod. 2013; 39(10): 1281-1286. DOI: 10.1016/j.joen.2013.06.012Zhou H.M., Shen Y., Zheng W., Li L., Zheng Y.F., Haapasalo M. Physical properties of 5 root canal sealers. J. Endod. 2013; 39(10): 1281-1286. DOI: 10.1016/j.joen.2013.06.012Viapiana R., Flumignan D.L., Guerreiro-Tanomaru J.M., Camilleri J., Tanomaru-Filho M. Physicochemical and mechanical properties of zirconium oxide and niobium oxide modified Portland cement-based experimental endodontic sealers. Int. Endod. J. 2014; 47(5): 437448. DOI: 10.1111/iej.12167Viapiana R., Flumignan D.L., Guerreiro-Tanomaru J.M., Camilleri J., Tanomaru-Filho M. Physicochemical and mechanical properties of zirconium oxide and niobium oxide modified Portland cement-based experimental endodontic sealers. Int. Endod. J. 2014; 47(5): 437448. DOI: 10.1111/iej.12167Colombo M., Poggio C., Dagna A., Meravini M.V., Riva P., Trovati F., Pietrocola G. Biological and physico-chemical properties of new root canal sealers. J. Clin. Exp. Dent. 2018; 10(2): e120-e126. DOI: 10.4317/jced.54548Colombo M., Poggio C., Dagna A., Meravini M.V., Riva P., Trovati F., Pietrocola G. Biological and physico-chemical properties of new root canal sealers. J. Clin. Exp. Dent. 2018; 10(2): e120-e126. DOI: 10.4317/jced.54548Tour Savadkouhi S., Fazlyab M. Discoloration potential of endodontic sealers: a brief review. Iran. Endod. J. 2016; 11(4): 250-254. DOI: 10.22037/iej.2016.20Tour Savadkouhi S., Fazlyab M. Discoloration potential of endodontic sealers: a brief review. Iran. Endod. J. 2016; 11(4): 250-254. DOI: 10.22037/iej.2016.20Ioannidis K., Beltes P., Lambrianidis T., Kapagianni-dis D., Karagiannis V. Crown discoloration induced by endodontic sealers: spectrophotometric measurement of Commission International de I'Eclairage's L*, a*, b* chromatic parameters. Oper. Dent. 2013; 38(3): E1-12. DOI: 10.2341/11-266-LIoannidis K., Beltes P., Lambrianidis T., Kapagianni-dis D., Karagiannis V. Crown discoloration induced by endodontic sealers: spectrophotometric measurement of Commission International de I'Eclairage's L*, a*, b* chromatic parameters. Oper. Dent. 2013; 38(3): E1-12. DOI: 10.2341/11-266-LTanomaru-Filho M., Cristine Prado M., Torres F.F.E., Viapiana R., Pivoto-Joao M.M.B., Guerreiro-Tanomaru J.M. Physicochemical Properties and Bioactive Potential of a New Epoxy Resin-based Root Canal Sealer. Braz. Dent. J. 2019; 30(6): 563-568. DOI: 10.1590/0103-6440201802861Tanomaru-Filho M., Cristine Prado M., Torres F.F.E., Viapiana R., Pivoto-Joao M.M.B., Guerreiro-Tanomaru J.M. Physicochemical Properties and Bioactive Potential of a New Epoxy Resin-based Root Canal Sealer. Braz. Dent. J. 2019; 30(6): 563-568. DOI: 10.1590/0103-6440201802861Versiani M.A., Abi Rached-Junior F.J., Kishen A., Pecora J.D., Silva-Sousa Y.T., de Sousa-Neto M.D.. Zinc Oxide Nanoparticles Enhance Physicochemical Characteristics of Grossman Sealer. J. Endod. 2016; 42(12): 1804-1810. DOI: 10.1016/j.joen.2016.08.023Versiani M.A., Abi Rached-Junior F.J., Kishen A., Pecora J.D., Silva-Sousa Y.T., de Sousa-Neto M.D.. Zinc Oxide Nanoparticles Enhance Physicochemical Characteristics of Grossman Sealer. J. Endod. 2016; 42(12): 1804-1810. DOI: 10.1016/j.joen.2016.08.023Javidi M., Zarei M., Ashrafpour E., Gharechahi M., Bagheri H. Post-treatment Flare-up Incidence after Using Nano Zinc Oxide Eugenol Sealer in Mandibular First Molars with Irreversible Pulpitis. J. Dent. (Shiraz). 2020; 21(4): 307-313. DOI: 10.30476/DENTJODS.2020.83231.1041Javidi M., Zarei M., Ashrafpour E., Gharechahi M., Bagheri H. Post-treatment Flare-up Incidence after Using Nano Zinc Oxide Eugenol Sealer in Mandibular First Molars with Irreversible Pulpitis. J. Dent. (Shiraz). 2020; 21(4): 307-313. DOI: 10.30476/DENTJODS.2020.83231.1041Javidi M., Zarei M., Omidi S., Ghorbani A., Gharechahi M., Shayani Rad M. Cytotoxicity of a new nano zinc-oxide eugenol sealer on murine fibroblasts. Iran Endod. J. 2015; 10(4): 231-235. DOI: 10.7508/iej.2015.04.004Javidi M., Zarei M., Omidi S., Ghorbani A., Gharechahi M., Shayani Rad M. Cytotoxicity of a new nano zinc-oxide eugenol sealer on murine fibroblasts. Iran Endod. J. 2015; 10(4): 231-235. DOI: 10.7508/iej.2015.04.004Javidi M., Dastmalchi P., Zarei M., Shayani Rad M., Ghorbani A. In vitro cytotoxicity of a new nano root canal sealer on human gingival fibroblasts. Iran Endod. J. 2017; 12(2): 220-225. DOI: 10.22037/iej.2017.43Javidi M., Dastmalchi P., Zarei M., Shayani Rad M., Ghorbani A. In vitro cytotoxicity of a new nano root canal sealer on human gingival fibroblasts. Iran Endod. J. 2017; 12(2): 220-225. DOI: 10.22037/iej.2017.43Crozeta B.M., Lopes F.C., Menezes Silva R., Silva-Sousa Y.T.C., Moretti L.F., Sousa-Neto M.D. Retreatability of BC Sealer and AH Plus root canal sealers using new supplementary instrumentation protocol during non-surgical endodontic retreatment. Clin. Oral. Investig. 2021; 25(3): 891-899. DOI: 10.1007/s00784-020-03376-4Crozeta B.M., Lopes F.C., Menezes Silva R., Silva-Sousa Y.T.C., Moretti L.F., Sousa-Neto M.D. Retreatability of BC Sealer and AH Plus root canal sealers using new supplementary instrumentation protocol during non-surgical endodontic retreatment. Clin. Oral. Investig. 2021; 25(3): 891-899. DOI: 10.1007/s00784-020-03376-4Zhekov K.I., Stefanova V.P. Retreatability of Bioceramic Endodontic Sealers: a Review. Folia. Med. (Plovdiv). 2020; 62(2): 258-264. DOI: 10.3897/folmed.62.e47690Zhekov K.I., Stefanova V.P. Retreatability of Bioceramic Endodontic Sealers: a Review. Folia. Med. (Plovdiv). 2020; 62(2): 258-264. DOI: 10.3897/folmed.62.e47690Kim K., Kim D.V., Kim S.Y., Yang S. A micro-computed tomographic study of remaining filling materials of two bioceramic sealers and epoxy resin sealer after retreatment. Restor. Dent. Endod. 2019; 44(2): e18. DOI: 10.5395/rde.2019.44.e18Kim K., Kim D.V., Kim S.Y., Yang S. A micro-computed tomographic study of remaining filling materials of two bioceramic sealers and epoxy resin sealer after retreatment. Restor. Dent. Endod. 2019; 44(2): e18. DOI: 10.5395/rde.2019.44.e18Ersev H., Yilmaz B., Dinpol M.E., Daglaroglu R. The efficacy of ProTaper Universal rotary retreatment instrumentation to remove single gutta-percha cones cemented with several endodontic sealers. Int. Endod. J. 2012; 45(8): 756-762. DOI: 10.1111/j.1365-2591.2012.02032.xErsev H., Yilmaz B., Dinpol M.E., Daglaroglu R. The efficacy of ProTaper Universal rotary retreatment instrumentation to remove single gutta-percha cones cemented with several endodontic sealers. Int. Endod. J. 2012; 45(8): 756-762. DOI: 10.1111/j.1365-2591.2012.02032.xKakoura F., Pantelidou O. Retreatability of root canals filled with Gutta percha and a novel bioceramic sealer: A scanning electron microscopy study. J. Conserv. Dent. 2018; 21(6): 632-636. DOI: 10.4103/JCD.JCD_228_18Kakoura F., Pantelidou O. Retreatability of root canals filled with Gutta percha and a novel bioceramic sealer: A scanning electron microscopy study. J. Conserv. Dent. 2018; 21(6): 632-636. DOI: 10.4103/JCD.JCD_228_18Oltra E., Cox T.C., LaCourse M.R., Johnson J.D., Paranjpe A. Retreatability of two endodontic sealers, EndoSequence BC Sealer and AH Plus: a micro-computed tomographic comparison. Restor. Dent. Endod. 2017; 42(1): 19-26. DOI: 10.5395/rde.2017.42.1.19Oltra E., Cox T.C., LaCourse M.R., Johnson J.D., Paranjpe A. Retreatability of two endodontic sealers, EndoSequence BC Sealer and AH Plus: a micro-computed tomographic comparison. Restor. Dent. Endod. 2017; 42(1): 19-26. DOI: 10.5395/rde.2017.42.1.19

The authors declare that there are no conflicts of interest present.