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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ksma</journal-id><journal-title-group><journal-title xml:lang="ru">Кубанский научный медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Kuban Scientific Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1608-6228</issn><issn pub-type="epub">2541-9544</issn><publisher><publisher-name>Kuban State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25207/1608-6228-2026-33-1-73-82</article-id><article-id custom-type="elpub" pub-id-type="custom">ksma-4144</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Пероральная эндоскопическая миотомия в лечении беременной пациентки с ахалазией кардии: клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Peroral endoscopic myotomy in the treatment of a pregnant achalasia patient: A clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0755-903X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Габриэль</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gabriel</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Габриэль Сергей Александрович — доктор медицинских наук, доцент, профессор кафедры хирургии № 3;</p><p>главный врач</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350055;</p><p>ул. Красных Партизан, д. 6/2, г. Краснодар, 350012</p></bio><bio xml:lang="en"><p>Sergey А. Gabriel — Dr. Sci. (Med.), Assoc. Prof., Professor at the Department of Surgery No. 3;</p><p>Chief Physician</p><p>Mitrofana Sedina str., 4, Krasnodar, 350055;</p><p>Krasnykh Partizan str., 6/2, Krasnodar, 350012</p></bio><email xlink:type="simple">Gabriel-sa@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8600-0532</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пенжоян</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Penzhoyan</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пенжоян Григорий Артемович — доктор медицинских наук, профессор, заведующий кафедрой акушерства, гинекологии и перинатологии № 2</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350055</p></bio><bio xml:lang="en"><p>Grigory А. Penzhoyan — Dr. Sci. (Med.), Prof., Head of the Department of Obstetrics, Gynecology, and Perinatology No. 2</p><p>Mitrofana Sedina str., 4, Krasnodar, 350055</p></bio><email xlink:type="simple">pga05@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2885-7674</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дурлештер</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Durleshter</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дурлештер Владимир Моисеевич — доктор медицинских наук, профессор, заведующий кафедрой № 3;</p><p>заместитель главного врача по хирургии</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350055;</p><p>ул. Красных Партизан, д. 6/2, г. Краснодар, 350012</p></bio><bio xml:lang="en"><p>Vladimir M. Durleshter — Dr. Sci. (Med.), Prof., Head of Department No. 3;</p><p>Deputy Chief Surgeon</p><p>Mitrofana Sedina str., 4, Krasnodar, 350055;</p><p>Krasnykh Partizan str., 6/2, Krasnodar, 350012</p></bio><email xlink:type="simple">durleshter59@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0903-1471</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беспечный</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bespechniy</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беспечный Михаил Васильевич — ассистент кафедры хирургии № 3;</p><p>врач-эндоскопист отделения</p><p>ул. им. Митрофана Седина, д. 4, г. Краснодар, 350055;</p><p>ул. Красных Партизан, д. 6/2, г. Краснодар, 350012</p></bio><bio xml:lang="en"><p>Mikhail V. Bespechniy — Teaching Assistant, Department of Surgery No. 3;</p><p>endoscopist, Endoscopy Department</p><p>Mitrofana Sedina str., 4, Krasnodar, 350055;</p><p>Krasnykh Partizan str., 6/2, Krasnodar, 350012</p></bio><email xlink:type="simple">mishasss4@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации;&#13;
Государственное бюджетное учреждение здравоохранения «Краевая клиническая больница № 2» Министерства здравоохранения Краснодарского края<country>Россия</country></aff><aff xml:lang="en">Kuban State Medical University, Ministry of Health of the Russian Federation;&#13;
Regional Clinical Hospital No. 2, Ministry of Health of Krasnodar Krai<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Kuban State Medical University, Ministry of Health of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2026</year></pub-date><volume>33</volume><issue>1</issue><fpage>73</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Габриэль С.А., Пенжоян Г.А., Дурлештер В.М., Беспечный М.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Габриэль С.А., Пенжоян Г.А., Дурлештер В.М., Беспечный М.В.</copyright-holder><copyright-holder xml:lang="en">Gabriel S.A., Penzhoyan G.A., Durleshter V.M., Bespechniy M.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ksma.elpub.ru/jour/article/view/4144">https://ksma.elpub.ru/jour/article/view/4144</self-uri><abstract><p>Введение. Ахалазия кардии — редкое заболевание пищевода, характеризующееся нарушением перистальтики и отсутствием нормального расслабления нижнего пищеводного сфинктера во время акта глотания.Описание клинического случая. Пациентка Т. 28 лет поступила в приемное отделение государственного бюджетного учреждения здравоохранения «Краевая клиническая больница № 2» Министерства здравоохранения Краснодарского края 29.02.2024 в порядке скорой медицинской помощи. Беременность 28 недель. При поступлении состояние пациентки тяжелое. Жалобы при поступлении: в течение последних 3 недель отмечает выраженную тошноту, рвоту до 10–15 раз в сутки, в том числе после приема жидкой пищи, слабость, головокружение. Из анамнеза: с 17 лет периодически возникают подобные жалобы. У гастроэнтеролога не наблюдалась. Последнее время данные симптомы связывала с беременностью. Предварительный диагноз: на основании жалоб пациентки, анамнеза, клинической картины заболевания и данных осмотра выставлен диагноз: аспирационная пневмония; ахалазия кардии III ст. Госпитализирована в реанимационное отделение. Заключение консилиума в составе: акушер-гинеколог, хирург, гастроэнтеролог, анестезиолог-реаниматолог, неонатолог: «Аспирационная пневмония. Ахалазия кардии III ст. Беременность 28 недель. Дисметаболическая энцефалопатия Вернике с легким вестибуло-атактическим синдромом и глазодвигательными нарушениями. Гестационный сахарный диабет, на диетотерапии, голодовой кетоз. Анемия 2 ст. Дефицит массы тела (индекс массы тела 17,3 кг/см2 )». Гемотрансфузия 2.03.2024. В связи с тяжестью состояния пациентки, наличием осложнений основного заболевания, необходимостью восстановления энтерального питания консилиумом было принято решение об оперативном лечении ахалазии кардии методом пероральной эндоскопической миотомии. Оперативное вмешательство было выполнено. В послеоперационном периоде пациентка находилась под динамическим наблюдением в течение 3 месяцев в женской консультации. За этот период пациентка поправилась на 5,5 кг. Родоразрешение произошло в срок через естественные родовые пути доношенного ребенка. Состояние новорожденного по шкале Апгар 8–9 баллов.Заключение. Применение пероральной эндоскопической миотомии у беременной пациентки является единичным случаем в мировой практике. Данная операция прошла успешно и никак не повлияла на дальнейшее развитие плода, вернула пациентку к физиологическому приему пищи и полноценному развитию плода.</p></abstract><trans-abstract xml:lang="en"><p>Background. Achalasia is a rare disorder characterized by the loss of esophageal peristalsis and the failure of the lower esophageal sphincter to relax during swallowing.Сase description. A 28-year-old female patient was urgently admitted to the Regional Clinical Hospital No. 2 (Ministry of Health of Krasnodar Krai) on February 29, 2024 at 28 weeks of pregnancy. Admitted in a serious condition, the patient presented with the following complaints: severe nausea, vomiting up to 10–15 times a day (which includes after eating liquid food), weakness, and dizziness for three weeks. Her medical history revealed recurring complaints since the age of 17; she had not been seen by a gastroenterologist. The patient attributed the latest symptoms to pregnancy. Based on her complaints, medical history, clinical picture, and examination data, the patient was preliminarily diagnosed with aspiration pneumonia and Type III esophageal achalasia. The patient was admitted to the intensive care unit. The opinion of the medical team, consisting of an obstetrician, a surgeon, a gastroenterologist, an intensivist, and a neonatologist is as follows: “aspiration pneumonia; Type III achalasia; 28 weeks pregnant; dysmetabolic Wernicke’s encephalopathy with a mild vestibular ataxia and oculomotor disorders; starvation ketosis in gestational diabetes mellitus in the context of a diet therapy; Grade 2 anemia; weight deficit (body mass index of 17.3 kg/cm2 ).” A blood transfusion was performed on March 2, 2024. Due to the severity of the patient’s condition, the presence of complications of the underlying disease, and the need to restore enteral nutrition, the medical team decided to surgically treat esophageal achalasia using peroral endoscopic myotomy. After the procedure, the patient received follow-up monitoring for three months at a maternity care center. During this period, the patient gained 5.5 kg. The baby was born full-term via natural birth, with an Apgar score of 8–9.Conclusion. The use of peroral endoscopic myotomy in a pregnant patient is a rare case in global practice. The procedure was successful and had no effect on the further development of the fetus, enabling the patient to resume normal eating habits and ensuring the healthy development of the fetus.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ахалазия кардии</kwd><kwd>дилатация пищевода</kwd><kwd>беременность</kwd><kwd>манометрия пищевода высокого разрешения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>esophageal achalasia</kwd><kwd>esophageal dilatation</kwd><kwd>pregnancy</kwd><kwd>high-resolution esophageal manometry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Oude Nijhuis RAB, Zaninotto G, Roman S, Boeckxstaens GE, Fockens P, Langendam MW, Plumb AA, Smout A, Targarona EM, Trukhmanov AS, Weusten B, Bredenoord AJ. 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