ksmaКубанский научный медицинский вестникKuban Scientific Medical Bulletin1608-62282541-9544Kuban State Medical Universityksma-632Research ArticleСтатьиАНАЛИЗ ПОКАЗАТЕЛЕЙ ДОППЛЕРОМЕТРИИ ВО II ТРИМЕСТРЕ БЕРЕМЕННОСТИ У ЖЕНЩИН С ВЫЯВЛЕННОЙ НА РАННИХ СРОКАХ РЕТРОХОРИАЛЬНОЙ ГЕМАТОМОЙANALYSIS OF UTEROPLACENTAL DOPPLER IN THE II TRIMESTER OF PREGNANCY IN WOMEN WITH RETROCHORIAL HEMATOMA DIAGNOSED IN THE EARLY STAGES OF PREGNANCYКузнецоваН. Б.KuznetsovaN. B.lauranb@inbox.ruЗаманскаяТ. А.ZamanskayaT. A.lauranb@inbox.ruБуштыреваИ. О.BushtyrevaI. O.lauranb@inbox.ruЗабановаЕ. А.ZabanovaE. A.lauranb@inbox.ruФГБОУ ВО Ростовский государственный медицинский университет Минздрава РоссииРоссияState Budget Educational Institution of Higher Professional Education «The Rostov State Medical University» of Ministry of Health of the Russian FederationRussian Federation20160112201668792Copyright © Кузнецова Н.Б., Заманская Т.А., Буштырева И.О., Забанова Е.А., 20162016Кузнецова Н.Б., Заманская Т.А., Буштырева И.О., Забанова Е.А.Kuznetsova N.B., Zamanskaya T.A., Bushtyreva I.O., Zabanova E.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://ksma.elpub.ru/jour/article/view/632

В работе представлен анализ показателей маточно-плацентарной гемодинамики и исходов беременности у женщин, имевших на ранних сроках угрозу прерывания беременности с формированием ретрохориальной гематомы. Было выявлено повышение интенсивности кровотока в правой маточной артерии по данным допплерометрии в 19-21 неделю у беременных, имевших ретрохориальную гематому в I триместре. Кровоток в левой маточной артерии в 19-21 неделю у беременных, имевших в I триместре ретрохориальную гематому объёмом >1 см3, оказался снижен. Маточно-плацентарный кровоток в бассейне правой маточной артерии достоверно повышен у беременных, получавших дидрогестерон, и у получавших микронизированный прогестерон. У беременных, имевших на ранних сроках ретрохориальную гематому объёмом >1 см3, отмечена достоверно более высокая частота оперативных родоразрешений.

The article presents an analysis of indicators of uteroplacental hemodynamics and outcomes of pregnancy of women with a threatened abortion in the early stages of pregnancy with the formation of a retrochorial hematoma. The increasing of the intensity of blood flow in the right uterine artery was found in pregnant women with retrochorial hematoma according to Doppler at 19-21 weeks of pregnancy. The blood flow appeared to be reduced in the left uterine artery at 19-21 weeks in pregnant women that occurred in 1 trimester retrochorial hematoma volume > 1 cm3. The analysis showed that pregnant women, who received dydrogesterone, and ones, who received micronized progesterone, had significantly elevated uteroplacental blood flow in the basin of the right uterine artery. There is significantly higher incidence of caesarean section in pregnant women who had the retrochorial hematoma volume >1 cm3 occurred in 1 trimester.

ретрохориальная гематомадопплерометрияматочно-плацентарная гемодинамикаисход беременностиretrochorial hematomaDoppleruteroplacental hemodynamicsoutcome of pregnancyReferencesНикитина Л. А., Демидова Е. М., Радзинский В. Е, Демидов Б. С, Самоходская Л. М. Роль матриксных белков, цитокинов и факторов ангиогенеза маточно-плацентарного комплекса в регуляции имплантации и плацентации. Акушерство и гинекология. - 2007. - 3. - 5-10.Никитина Л. А., Демидова Е. М., Радзинский В. Е, Демидов Б. С, Самоходская Л. М. Роль матриксных белков, цитокинов и факторов ангиогенеза маточно-плацентарного комплекса в регуляции имплантации и плацентации. Акушерство и гинекология. - 2007. - 3. - 5-10.Abu-Yousef M. M., Bleicher J. J., Williamson R. A., Weiner C. P. Subchorionic hemorrhage: sonographic diagnosis and clinical significance. American Journal of Roentgenology. - 1987. - 149. -737-740.Abu-Yousef M. M., Bleicher J. J., Williamson R. A., Weiner C. P. Subchorionic hemorrhage: sonographic diagnosis and clinical significance. American Journal of Roentgenology. - 1987. - 149. -737-740.Bennett G. L., Bromley B., Lieberman E., Benacerraf B. R. Subchorionic hemorrhage in first-trimester pregnancies: prediction of pregnancy outcome with sonography. Radiology. - 1996 Sep. -200. - 3. - 803-806.Bennett G. L., Bromley B., Lieberman E., Benacerraf B. R. Subchorionic hemorrhage in first-trimester pregnancies: prediction of pregnancy outcome with sonography. Radiology. - 1996 Sep. -200. - 3. - 803-806.Ben-Haroush A, Yogev Y, Mashiach R, Meizner I. Pregnancy outcome of threatened abortion with subchorionic hematoma: possible benefit of bed-rest? Isr Med Assoc J. - 2003 Jun - 5 (6): 422-424.Ben-Haroush A, Yogev Y, Mashiach R, Meizner I. Pregnancy outcome of threatened abortion with subchorionic hematoma: possible benefit of bed-rest? Isr Med Assoc J. - 2003 Jun - 5 (6): 422-424.Bushtyreva I. O., Milovanov A. P., Kuznetsova N. B., Barinova V. V., Dmitrieva M. P. Pregnancy outcomes in pregnant women with retrochorial hematoma in the first trimester. 14th World Congress in Fetal Medicine, AbstractsBushtyreva I. O., Milovanov A. P., Kuznetsova N. B., Barinova V. V., Dmitrieva M. P. Pregnancy outcomes in pregnant women with retrochorial hematoma in the first trimester. 14th World Congress in Fetal Medicine, AbstractsGoldstein S. R., Subramanyam B. R., Raghavendra B. N., Horii S. C., Hilton S. Subchorionic bleeding in threatened abortion: sonographic findings and significance. American Journal of Roentgenology. - 1983. - 141. - 975-978.Goldstein S. R., Subramanyam B. R., Raghavendra B. N., Horii S. C., Hilton S. Subchorionic bleeding in threatened abortion: sonographic findings and significance. American Journal of Roentgenology. - 1983. - 141. - 975-978.Kyser K. L. Meta-analysis of subchorionic hemorrhage and adverse pregnancy outcomes. Proc Obstet Gynecol. - 2012. - 2. - 4.Kyser K. L. Meta-analysis of subchorionic hemorrhage and adverse pregnancy outcomes. Proc Obstet Gynecol. - 2012. - 2. - 4.Lan X., Zhaolian W., Yunxia C. Symptoms of an Intrauterine Hematoma Associated with Pregnancy Complications: A Systematic Review. PLoS One. - 2014. - 9. - 11.Lan X., Zhaolian W., Yunxia C. Symptoms of an Intrauterine Hematoma Associated with Pregnancy Complications: A Systematic Review. PLoS One. - 2014. - 9. - 11.Leite J., Rossi A. C. A very large first-trimester hematoma is associated with a 46% risk of adverse pregnancy outcome (spontaneous abortion and premature rupture of membranes) Prognosis of very large first-trimester hematomas. J Ultrasound Med - 2006 Nov. - 25. - 11. - 1441-1445.Leite J., Rossi A. C. A very large first-trimester hematoma is associated with a 46% risk of adverse pregnancy outcome (spontaneous abortion and premature rupture of membranes) Prognosis of very large first-trimester hematomas. J Ultrasound Med - 2006 Nov. - 25. - 11. - 1441-1445.Mantoni M., Pedersen J. F. Intrauterine haematoma. An ultrasonic study of threatened abortion. Br J Obstet Gynaecol. -1981 Jan. - 88. - 1. - 47-51.Mantoni M., Pedersen J. F. Intrauterine haematoma. An ultrasonic study of threatened abortion. Br J Obstet Gynaecol. -1981 Jan. - 88. - 1. - 47-51.Nagy S., Bush M., Stone J., Lapinski R. H., Gardo S. Clinical significance of subchorionic and retroplacental hematomas detected in the first trimester of pregnancy. Obstet Gynecol. -2003. - 102. - 94-100.Nagy S., Bush M., Stone J., Lapinski R. H., Gardo S. Clinical significance of subchorionic and retroplacental hematomas detected in the first trimester of pregnancy. Obstet Gynecol. -2003. - 102. - 94-100.van Oppenraaij R. H., Jauniaux E., Christiansen O. B., Horcajadas J. A., Farquharson R. G., Exalto N. Predicting adverse obstetric outcome after early pregnancy events and complications: a review. Hum Reprod Update. - 2009 Jul-Aug. - 15. - 4. -409-421.van Oppenraaij R. H., Jauniaux E., Christiansen O. B., Horcajadas J. A., Farquharson R. G., Exalto N. Predicting adverse obstetric outcome after early pregnancy events and complications: a review. Hum Reprod Update. - 2009 Jul-Aug. - 15. - 4. -409-421.Özkaya E., Altay M., Geliçen O. Significance of subchorionic haemorrhage and pregnancy outcome in threatened miscarriage to predict miscarriage, pre-term labour and intrauterine growth restriction. J Obstet Gynaecol. - 2011. - 31. - 210-212.Özkaya E., Altay M., Geliçen O. Significance of subchorionic haemorrhage and pregnancy outcome in threatened miscarriage to predict miscarriage, pre-term labour and intrauterine growth restriction. J Obstet Gynaecol. - 2011. - 31. - 210-212.Pedersen J. F., Mantoni M. Large intrauterine haematomata in threatened miscarriage. Frequency and clinical consequences. Br J Obstet Gynaecol. - 1990 Jan. - 97. - 1. - 75-77.Pedersen J. F., Mantoni M. Large intrauterine haematomata in threatened miscarriage. Frequency and clinical consequences. Br J Obstet Gynaecol. - 1990 Jan. - 97. - 1. - 75-77.Pedersen J. F., Mantoni M. Prevalence and significance of subchorionic hemorrhage in threatened abortion: a sonographic study. Am J Roentgenol. - 1990 Mar. - 154. - 3. - 535-537.Pedersen J. F., Mantoni M. Prevalence and significance of subchorionic hemorrhage in threatened abortion: a sonographic study. Am J Roentgenol. - 1990 Mar. - 154. - 3. - 535-537.Sauerbrei E. E., Pham D. H. Placental abruption and subchorionic hemorrhage in the first half of pregnancy: US appearance and clinical outcome. Radiology. -1986 Jul. - 160. -109-112.Sauerbrei E. E., Pham D. H. Placental abruption and subchorionic hemorrhage in the first half of pregnancy: US appearance and clinical outcome. Radiology. -1986 Jul. - 160. -109-112.Soldo V., Cutura N., Zamurovic M. Threatened miscarriage in the first trimester and retrochorial hematomas: sonographic evaluation and significance. Clin Exp Obstet Gynecol. - 2013. -40. - 4. - 548-550.Soldo V., Cutura N., Zamurovic M. Threatened miscarriage in the first trimester and retrochorial hematomas: sonographic evaluation and significance. Clin Exp Obstet Gynecol. - 2013. -40. - 4. - 548-550.Stabile I., Campbell S., Grudzinskas J. G. Threatened miscarriage and intrauterine hematomas. Sonographic and biochemical studies. J Ultrasound Med. 1989 Jun. - 8. - 6. -289-292.Stabile I., Campbell S., Grudzinskas J. G. Threatened miscarriage and intrauterine hematomas. Sonographic and biochemical studies. J Ultrasound Med. 1989 Jun. - 8. - 6. -289-292.Şükür Y. E., Gög G., Köse O., Açmaz G., Özmen B., Atabekoğlu C. S., Kog A., Söylemez F. The effects of subchorionic hematoma on pregnancy outcome in patients with threatened abortion. J Turk Ger Gynecol Assoc. - 2014 Dec. - 15. - 4. -239-242.Şükür Y. E., Gög G., Köse O., Açmaz G., Özmen B., Atabekoğlu C. S., Kog A., Söylemez F. The effects of subchorionic hematoma on pregnancy outcome in patients with threatened abortion. J Turk Ger Gynecol Assoc. - 2014 Dec. - 15. - 4. -239-242.Tuuli M. G., Norman S. M., Odibo A. O., Macones G. A., Cahill A. G. Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysis. Obstet Gynecol. - 2011 May. - 117. - 5. - 1205-1212.Tuuli M. G., Norman S. M., Odibo A. O., Macones G. A., Cahill A. G. Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysis. Obstet Gynecol. - 2011 May. - 117. - 5. - 1205-1212.

The authors declare that there are no conflicts of interest present.