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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ksma</journal-id><journal-title-group><journal-title xml:lang="ru">Кубанский научный медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Kuban Scientific Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1608-6228</issn><issn pub-type="epub">2541-9544</issn><publisher><publisher-name>Kuban State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25207/1608-6228-2017-24-4-109-114</article-id><article-id custom-type="elpub" pub-id-type="custom">ksma-832</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ВОЗМОЖНОСТИ И ПЕРСПЕКТИВЫ СИСТЕМНОЙ КОМПЛЕКСНОЙ ОЦЕНКИ СОСТОЯНИЯ ИММУНИТЕТА ДЕТЕЙ, СТРАДАЮЩИХ ЯЗВЕННОЙ БОЛЕЗНЬЮ ДВЕНАДЦАТИПЕРСТНОЙ КИШКИ</article-title><trans-title-group xml:lang="en"><trans-title>OPPORTUNITIES AND PROSPECTS OF THE SYSTEM INTEGRATED ASSESSMENT OF IMMUNITY OF CHILDREN SUFFERING ULCER DUODENUM</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полянский</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyanskiy</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Контактная информация: Полянский Алексей Владимирович</p><p>350001, г. Краснодар, ул. 2-й проезд Шевченко 58; тел.: 8-903-4-111-340</p></bio><bio xml:lang="en"><p>Corresponding author:  Alexei V. Polyanskiy</p><p>58, 2-nd passage Shevchenko Street, Krasnodar, 350001; tel.: 8-903-4-111-340</p></bio><email xlink:type="simple">NVKotova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурлуцкая</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Burlutskaya</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра педиатрии №2 </p><p>350063, г. Краснодар, ул. Седина, 4 </p></bio><bio xml:lang="en"/><email xlink:type="simple">kafedragped2@lenta.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУЗ «Детская краевая клиническая больница» департамента здравоохранения Краснодарского Края</institution><country>Россия</country></aff><aff xml:lang="en"><institution>GUZ «Regional Clinical Children's Hospital»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University of the Ministry of Health Care of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>10</day><month>10</month><year>2017</year></pub-date><volume>0</volume><issue>4</issue><fpage>109</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Полянский А.В., Бурлуцкая А.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Полянский А.В., Бурлуцкая А.В.</copyright-holder><copyright-holder xml:lang="en">Polyanskiy A.V., Burlutskaya A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ksma.elpub.ru/jour/article/view/832">https://ksma.elpub.ru/jour/article/view/832</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить некоторые закономерности изменений систем иммунитета и резистентности у детей больных язвой duodenum. На основе системного патогенетического подхода разработать систему комплексной оценки состояния иммунитета ребенка с язвой duodenum.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено клинико-иммунологическое обследование 114 в возрасте 5-14 лет, страдающих язвой duodenum. Контрольную группу составили 30 практически здоровых детей того же возраста. Исследование венозной крови проводили на следующий день после госпитализации и после курса соответствующего лечения перед выпиской. Методом математического анализа обоснована "факторная" структура иммунной системы в норме и при язве duodenum.</p></sec><sec><title>Результаты</title><p>Результаты. На разных этапах развития болезни меняется количество и структура связей между компонентами внутри иммунной системы и ее взаимоотношение с другими системами.</p></sec><sec><title>Заключение</title><p>Заключение. Выявленные особенности – нормальная физиологическая реакция иммунной системы на развитие иммунологического процесса в слизистой оболочке duodenum. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To explore some regularities of the immune system and resistance in children with ulcer duodenum. On the basis of systemic pathogenetic approach to develop a system of integrated assessment of the immunity of the child with the ulcer duodenum.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A clinical and immunological study of 114 children aged 5-14 years, suffering from an ulcer duodenum. The control group consisted of 30 healthy children of similar age. Investigation of venous blood were performed on the day after admission and after a course of appropriate treatment before discharge. By mathematical analysis of unsubstantiated "factor" structure of the immune system in normal and ulcer duodenum.</p></sec><sec><title>Results</title><p>Results. At different stages of the disease varies the amount and structure of relations between the components within the immune system and its relationship with other systems. Conclusion. These peculiarities – a normal physiological response of the immune system to develop an immunological process in the mucosa of duodenum. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>язва duodenum</kwd><kwd>"факторная" структура иммунной системы</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ulcer duodenum</kwd><kwd>"factor" structure of the immune system</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Земсков А.М., Земсков В.М., Есауленко И.Э., Земсков М.А., Тонких Р.В., Злоедов В.И. 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