ksmaКубанский научный медицинский вестникKuban Scientific Medical Bulletin1608-62282541-9544Kuban State Medical University10.25207/1608-6228-2017-24-4-185-190ksma-846Research ArticleОБЗОРЫREVIEWСИНДРОМ НЕПЕРЕНОСИМОСТИ ГИСТАМИНА У ДЕТЕЙSYNDROME OF CHILDREN S HISTAMINE INTOLERANCEБурлуцкаяА. В.BurlutskaiaA. V.

Кафедра педиатрии № 2,

Контактная информация: Фирсова Виолетта Николаевна 2,

350063, г. Краснодар, ул. Седина, 4; тел.: 8 (918) 443-20-73 

Department of pediatrics № 2 

Corresponding author: Violetta N. Firsova

4 Sedina Street, Krasnodar, 350063; tel.: 8 (918) 443-20-73

gped2@lenta.ruФирсоваВ. Н.FirsovaV. N.

Кафедра педиатрии № 2,

350063, г. Краснодар, ул. Седина, 4

Department of pediatrics № 2 

4 Sedina Street, Krasnodar, 350063

ФГБОУ ВО «Кубанский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияKuban State Medical University of the Ministry of Health Care of the Russian FederationRussian Federation20171110201704185190Copyright © Бурлуцкая А.В., Фирсова В.Н., 20172017Бурлуцкая А.В., Фирсова В.Н.Burlutskaia A.V., Firsova V.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ksma.elpub.ru/jour/article/view/846 Цель

 Цель. Обратить внимание на актуальность проблемы для дальнейшего более глубокого изучения заболеваний у детей, в основе которых лежит нарушение обмена гистамина в организме, а именно повышение уровня внеклеточного гистамина. Изучить синдром непереносимости гистамина, вопросы диагностики и лечения недостаточности диаминоксидазы.

 Результаты

 Результаты. Понимание этиологии и патогенеза синдрома непереносимости гистамина, изучение вопроса диагностики и лечения недостаточности диаминоксидазы дает новые возможности в успешном лечении, а главное предупреждении пищевой гиперчувствительности у детей. 

Aim

Aim. The purpose of the study: to pay attention to the urgency of the problem for further deeper study of diseases in children, which is based on the violation of histamine metabolism in the body, namely, increase in the level of extracellular histamine. To study the syndrome of intolerance to histamine (CIS), the diagnosis and treatment of diaminoxidase deficiency (DAO).

Results

Results. Understanding the etiology and pathogenesis of the CIS, studying the diagnosis and treatment of DAO deficiency gives new opportunities in successful treatment, and most importantly prevention of food hypersensitivity in children.

гистаминдиаминоксидаза (ДАО)синдром непереносимости гистамина (СНГ)ГистДАОкожный прик-тестзаместительная терапиятест Гистамин 50histaminediaminoksidazy (DAO)a syndrome of intolerance to histamine (SIH)GISTDAskin prick testtherapytest Histamine 50ReferencesКампс А.Р. Клинические аспекты питания и непереносимости гистамина у детей с симптомами хронического нарушения пищеварения. – М.: 2015. 156 с.Kamps Antonio Rossel'. Klinicheskie aspekty pitanija i neperenosimosti gistamina u detej s simptomami hronicheskogo narushenija pishhevarenija / Antonio Rossel' Kamps. – Moskva, 2015; 156р.Asher M.L. ISAAC Steering Committee. Clin. Exp. Allergy. 1998; 28(5): 52 -66. 3. Humbert M. Editorial 100* International Conference of the Amer. Thoracic Society. SCAN. 2004: 3.Asher M. L. ISAAC Steering Committee. Clin. Exp. Allergy. 1998. 28 (5): 52 -66.Asher M.L. International Study of Asthma and Allergies in Childhood (ISAAC). Amer. Thoracic Society. S CAN. 2004: 3.Humbert M. 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The authors declare that there are no conflicts of interest present.