TREATMENT OF CHRONIC GENERALIZED PERIODONTITIS WITH THE USE OF BACTERIOTOXIC PHOTOTHERAPY AND SUBSEQUENT SURGICAL TREATMENT WITH THE USE OF OSTEOPLASTIC MATERIAL BIO-GENE

Aim. To increase the effectiveness of treatment of patients with chronic generalized periodontitis by using bacteriotoxic phototherapy with subsequent surgical treatment with the use of osteoplastic material bio-gene.

Materials and methods. 60 people were observed: 30 people in the main group, and 30 people in the control group. All patients of the main group before the surgical treatment underwent bacteriotoxic phototherapy with photosensitizer "fotolon", diluted according to the instruction. Then followed a surgical treatment of chronic generalized periodontitis with the use of an osteoplastic material Bio-Gen. Patients of the control group were treated with a well-known conservative method. The state of microcirculation of periodontal tissue was studied in all patients applying the method of laser Doppler flowmetry. The composition of microflora of the contents of periodontal pockets was determined before and after the treatment.

Results. As a result of our comprehensive treatment of chronic generalized periodontitis (the main group) with the use of bacteriotoxic phototherapy with ‘fotolon’ with subsequent surgical treatment with the use of osteoplastic material bio-gene after 12 months, the data of laser Doppler flowmetry showed an improvement in the microcirculation of periodontal tissues. After the treatment, a significant decrease in the number of microorganisms was observed. There was no significant improvement in the microcirculation of periodontal tissue in the control group of patients, as well as any decrease in the number of basic parodontopathogenic species of microorganisms.

Conclusion. Combined application of bacteriotoxic phototherapy and surgical treatment with the use of osteoplastic drug bio-gene in the treatment of chronic generalized periodontitis demonstrates a pronounced therapeutic effect, which consists in improvement of microcirculation of periodontal tissues. Microbiological research in all patients after the treatment showed high efficiency of this method in relation to the main types of parodontopathogenic microorganisms.

1. Kankanyan A.P. Periodontal diseases: new approaches in aetiology, pathogenesis, diagnostics, treatment, and prevention. Erevan: Tigran Mec Publ.; 2006. 358 p. (In Russ.).

2. Yanushevich O.O. Periodontal diseases. Modern take on clinicodiagnostic and medical aspects. Moscow: Geotar-Media Publ.; 2010. 160 p. (In Russ.).

3. Orekhova L.Yu. Problems of dental care for young people (literature review). Parodontologiya. 2014; 2(71): 3-5. (In Russ., English abstract).

4. Tsepov L.M. Some aspects of etiology and pathogenesis of chronic inflammatory generalized diseases of periodontal (literature review). Parodontologiya. 2005; 2: 3-6. (In Russ., English abstract).

5. Bezrukova I.V., Grudyanov A.I. Agressive forms of periodontitis. Moscow. OOO "Medicinskoe informacionnoe agentstvo" Publ.; 2002. 127 p. (In Russ.).

6. Zhulev E.N., Fedoseeva I.G., Alekseeva N.A. The status of microcirculation of parodontium tissues in patients with gum recession and artifi crowns. Sovremennye problemy nauki i obrazovaniya. 2015; 4: 47-53. (In Russ., English abstract).

7. Bychkova N.P., Skorikova L.A., Volkov V.A., Lapina N.V. Dynamics of microcirculation of parodontium tissues indices when reconstructing the bottom of the upper jaw sinus with the use of the osteoplastic material Bio-Gen. Kubanskij nauchnyj medicinskij vestnik. 2017; 1: 15-21. (In Russ., English abstract).

8. Bychkova N.P., Skorikova L.A. Dynamics of microcirculation of parodontial tissue in people with chronic generalized periodontitis. Kubanskij nauchnyj medicinskij vestnik. 2016; 4: 20-23. (In Russ., English abstract).

9. Grudyanov A.I. Quantitative assessment of microbiocenosis of oral cavity in periodontal diseases. Parodontologiya. 2011; 2(59): 19-22. (In Russ., English abstract).

10. Kuznetsov E.A., Tsarev V.N., Davydova M.M. Mikrob flora of oral cavity and its role in pathologic processes development. Moscow. Medicina Publ.; 1995. 73 p. (In Russ.).

11. Pavlenko A.V., Dmitrieva E.A., Luzin V.I. Histological structure of a regenerate when filling a bone defect with easygraft and tricalcium phosphate. Morfologiya. 2011; 5(4): 49-54. (In Russ., English abstract).

12. Ohba S., Wang W., Itoh S., Takagi Y. Acceleration of new bone formation by an electrically polarized hydroxyapatite microgranule / platelet-rich plasma composite. Rosenquist Acta Biomateriale. 2012; 8(5): 2778-2787.

13. Ladd A.L., Wirsing K. Bone Graft Substitutes. Principles and Practice of Wrist Surgery. 2010; 277-288.