Preview

Kuban Scientific Medical Bulletin

Advanced search

THE IMMUNOPROPHYLAXIS OF ROTAVIRUS INFECTIONS IN KRASNODAR

https://doi.org/10.25207/1608-6228-2018-25-5-152-155

Abstract

Aim. This research was performed to study the specific immunoprophylaxis of rotavirus infection among child population in Krasnodar.

Materials and methods. There was conducted the analysis of 2386 medical records of patients who were immunized against the rotavirus infection by the pentavalent reassortant vaccine "Rotatec" for the period of 2013-2017, the assessment of the incidence of acute intestinal infections (AII) and rotavirus infection among vaccinated and unvaccinated children of the first two years of life as well as a comparative analysis of primary prophylaxis of rotavirus infection with the incidence of rotavirus infection according to data of Rospotrebnadzor for the study period.

Results. Coverage of the vaccination against rotavirus infection among children in Krasnodar for the period of 2013−2017 was 5,6 % of the target cohort which is not enough to reduce the incidence of rotavirus gastroenteritis. There was demonstrated the efficacy and safety of rotavirus vaccine. During the study period vaccinated children were 2.5 times less likely to suffer from AII. No cases of rotavirus infection were reported among the vaccinated respondents.

Conclusion. The leading role of rotavirus infection in severe forms of acute gastroenteritis in children of the first 5 years of life as well as the high efficiency of vaccine prophylaxis gives hope that vaccination against rotavirus infection will be included in the Russian national calendar of preventive vaccinations everywhere in the nearest future. 

About the Authors

D. V. Sutovskaya
Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation
Russian Federation
Sedina str., 4, Krasnodar, 350063


A. V. Burlutskaya
Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation
Russian Federation
Sedina str., 4, Krasnodar, 350063


L. V. Dubova
Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation
Russian Federation
Sedina str., 4, Krasnodar, 350063


E. I. Tunikova
Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation
Russian Federation
Sedina str., 4, Krasnodar, 350063


V. V. Kulikova
Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation
Russian Federation
Sedina str., 4, Krasnodar, 350063


References

1. Distribution of the estimated deaths among children under 5 years of age, from diseases that are preventable by vaccination in 2008. [Electronic resource]. [cited 2017 jul. 1.]. Access mode: http//www.who.int/immunization/monitoring-vaccination-surveillance/burden/estimates/en/.

2. Lanata C.F., Walker C.L., Olascoaga A.C., Torres C.X., Aryee M.J., Black R.E. Child Health Epidemiology Reference Group of the World Health Organization and UNICEF. Globalcauses of diarrheal disease mortality in children ˂5 years of age: a systematic review. PLoSOne. 2013; 8 (9): 72788. DOI: 10.1371/journal.pone.0072788.

3. Tate J.E., Burton A.H., Boschi-Pinto C., et al. 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccinations programmes: a systematic review and meta-analysis. Lancet Infect Dis. 2012; 12(2): 136-141. DOI: 10.1016/S1473-3099(11)70253-5.

4. WHO Global rotavirus surveillance network – a strategic review of the first 5 years (2008-2012). Wkly Epidemiol Rec. 2014; 89(30): 340-344.

5. Lobzin Y.V., Kharit S.M., Goveia M.G., et al. Burden of childhood rotavirus disease in the outpatient setting of the Russian Federation. Pediatr infect Dis. J. 2017; 36(5): 472-476. DOI: 10.1097/INF.0000000000001472.

6. Gosudarstvennyj doklad «O sostoyanii sanitarnoehpidemiologicheskogo blagopoluchiya naseleniya v Rossijskoj Federacii v 2016 godu». Moskva: sluzhba po nadzoru v sfere zashchity prav potrebitelej i blagopoluchiya cheloveka; 2017. 220s. (In Russ.).

7. Rotavirus vaccines: an update. Wkly Epidemiol Rec. 2009; 84(50): 533-540.

8. Loharikar A, Dumolard L, Chu S, et al. Status of new vaccine introduction – worldwide, September 2016. Morb Mortal Wkly Rep. 2016; 65(41): 1136-1140. DOI: 10.15585/mmwr.mm6541a3.

9. WHO vaccine-preventable diseases: monitoring system. 2016 global summary. [Electronic resource]. [cited 2017 Jul. 8. ]. Access mode: hppt://apps.who.int/immunization_monitoring/globalssummary/schedules.

10. Soares-Weiser K., MacLehose H., Bergman H., BenAharon I., Nagpal S., Goldberg E., Pitan F., Cunliffe N. Vaccines for preventing rotavirus diarrhoea: vaccines in use. Cochr. Database Syst. Rev. 2012; 14(11): CD008521. DOI: 10.1002/14651858. CD008521.pub3. 11. Tate J.E., Parashar U.D. Rotavirus vaccines in routine use. Clin. Infect. Dis. 2014; 59: 1291-1301. DOI: 10.1093/cid/ciu564.


Review

For citations:


Sutovskaya D.V., Burlutskaya A.V., Dubova L.V., Tunikova E.I., Kulikova V.V. THE IMMUNOPROPHYLAXIS OF ROTAVIRUS INFECTIONS IN KRASNODAR. Kuban Scientific Medical Bulletin. 2018;25(5):152-155. (In Russ.) https://doi.org/10.25207/1608-6228-2018-25-5-152-155

Views: 387


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1608-6228 (Print)
ISSN 2541-9544 (Online)