DYNAMICS OF LEVEL B-ENDORPHINS AT MODELLING OF THE ISCHEMIC STROKE AT RATS
Abstract
The problem of treatment of the ischemic stroke (IS) is actual in modern medicine. In work an attempt of creation of model of cerebral ischemia at rats with possibility of application of TES-therapy is made. Experiments are made on 130 rats who were divided into 4 groups: 1 - control, 2 - IS modeling, 3 - application of TES-therapy and IS modeling, 4 -modeling of IS and TES-therapy application. In serum of blood investigated level β-endorphins for 1, 3, 7 and 14 days. As a result of the conducted research it is established that the contents β-endorphins decreases throughout the entire period of supervision. Preliminary carrying out TES-therapy and its carrying out after modeling of IS stimulates a stress - limiting system and prevents level falling β-endorphins the entire period of supervision over animals.
About the Authors
A. I. Trofimenko
Kuban state medical university of the Ministry of health care and social development of the Russian Federation
Russian Federation
Russian Federation
A. Kh. Kade
Kuban state medical university of the Ministry of health care and social development of the Russian Federation
Russian Federation
Russian Federation
F. A. Nehaj
Kuban state medical university of the Ministry of health care and social development of the Russian Federation
Russian Federation
Russian Federation
V. P. Lebedev
Pavlov Institute of physiology Russian academy of sciences electrostimulation center transcranial
Russian Federation
Russian Federation
V. D. Levichkin
Kuban state medical university of the Ministry of health care and social development of the Russian Federation
Russian Federation
Russian Federation
S. A. Zanin
Kuban state medical university of the Ministry of health care and social development of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Trofimenko A.I., Kade A.Kh., Nehaj F.A., Lebedev V.P., Levichkin V.D., Zanin S.A. DYNAMICS OF LEVEL B-ENDORPHINS AT MODELLING OF THE ISCHEMIC STROKE AT RATS. Kuban Scientific Medical Bulletin. 2014;(3):115-118. (In Russ.)
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