Monitoring of cytokine level moisture in aqueous chamber during surgical debridement of observational penetrating wounds of eye cornea with nickelid titanium suture material

Abstract

Comparative assessment of cytokine profile status in aqueous chamber moisture with experimental rabbits while use of traditional suture material and nickelid titanium monolithic fibers with penetrating wounds of eye cornea has been done. It has been approved within the course of examinations (3, 7, 30 days) that use of conventional suture material does not influence on FNOα concentration; concentration of IL1β is certainly increases from the 3rd day of examinations and remains unchanged up to the end of monitoring; IL2 concentration probably significant increases to the 30th day of examination and concentration of IL10 increased in early period (on the 3rd day), is declining to the same level with noninvolved animals. in any period of examinations after suturing of eye cornea with nickelid titanium monolithic fibers of rabbits in experimental group, level of IL2, IL10, FNOα was fixed on the reference value level, except of obvious reduction of the latter (IL10, FNOα) in early periods of monitoring (3rd day). Herewith, certainly increased IL1β concentration that was studied dynamically, was less expressed compared to that appeared while use of conventional suture materials with postoperative rabbits. Analysis of the obtained data generally grounds advisability and preferable ness of use of suture material of nickelid titanium in cases of penetrating eye cornea wounds that has been confirmed by clinical data in this experiment.