A clinical report of Burkitt’s lymphoma
https://doi.org/10.25207/1608-6228-2020-27-4-161-168
Abstract
Aim. A clinical analysis of Burkitt’s lymphoma (BL) in a 4 years-old female child.
Materials and methods. A retrospective analysis was conducted for the history, disease’s course, laboratory and instrumental diagnosis and treatment in patient B. with BL, 4 years old.
Results. A 4-yo patient was diagnosed with BL spread to bone marrow, CNS, lymph nodes, both kidneys and spleen. Leukocytosis in common blood profile. Elevated lactate dehydrogenase (LDH) and C-reactive protein (CRP) in biochemical blood profile. Neck lymphadenopathy, mediastinum in computed tomography (CT). Splenomegaly. Multifocal lesion of both kidneys. Retroperitoneal lymphadenopathy. Positive clinical dynamics (normalisation of body weight) is observed with background therapy, LDH 335 U/L in biochemical blood profile, reduced multifocal kidney lesion and spleen size in CT.
Conclusion. A clinical case of Burkitt’s lymphoma is reported affecting the bone marrow, CNS, lymph nodes, both kidneys and spleen. Intensive polychemotherapy allowed stabilisation of the patient and containment of oncological processes.
About the Authors
A. V. Burlutskaya
Kuban State Medical University
Russian Federation
Russian Federation
Alla V. Burlutskaya — Dr. Sci. (Med.), Assoc. Prof., Head of the Chair of Paediatrics No. 2
Mitrofanа Sedinа str., 4, Krasnodar, 350063
N. S. Kovalenko
Kuban State Medical University
Russian Federation
Russian Federation
Natalya S. Kovalenko — Clinical Resident (1st year), Chair of Paediatrics No. 2
Mitrofanа Sedinа str., 4, Krasnodar, 350063
A. V. Statova
Kuban State Medical University
Russian Federation
Russian Federation
Anastasia V. Statova — Cand. Sci. (Med.), Assoc. Prof., Chair of Paediatrics No. 2
Mitrofanа Sedinа str., 4, Krasnodar, 350063
Yu. V. Brisin
Children’s Regional Clinical Hospital
Russian Federation
Russian Federation
Yurii V. Brisin — Research Assistant, Chair of Paediatrics No. 2, Kuban State Medical University; Physician, Oncology and Haematology Unit, Children’s Regional Clinical Hospital
Pobedy square, 1, Krasnodar, 350000
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Review
For citations:
Burlutskaya A.V., Kovalenko N.S., Statova A.V., Brisin Yu.V. A clinical report of Burkitt’s lymphoma. Kuban Scientific Medical Bulletin. 2020;27(4):161-168. (In Russ.) https://doi.org/10.25207/1608-6228-2020-27-4-161-168
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