Preview

Kuban Scientific Medical Bulletin

Advanced search

Aspects of the surgical treatment of secondary hyperparathyroidism in patients with chronic renal failure are on dialysis replacement therapy program

Abstract

The article is devoted to study of efficacy of surgical methods of treatment of secondary hyperparathyroidism which is refractory to therapy using active metabolites of D vitamin in patients with stage V chronic renal disease receiving treatment with program hemodialysis. In some cases the surgical treatment of the advanced stage of secondary hyperparathyroidism, PTH reduction was not observed, but patients reported clearly the disappearance or reduction of the pain in the bones and joints and also the normalization of calcium phosphorus metabolism. We are adhere to surgical treatment method consisting in removing of enlarged parathyroid glands with further conservative therapy that helps to avoid postoperative hypoparathyroidism, normalize the levels of parathyroid hormone and improves the quality of life of patients.

About the Authors

V. Yu. Mykhaylichenko
Medical academy named after S. I. Georgievskiy, the Federal state autonomous educational establishment of higher education «Crimean federal university named after V. I. Vernadsky» Ministry of education and science of the Russian Federation
Russian Federation


N. E. Karakursakov
Medical academy named after S. I. Georgievskiy, the Federal state autonomous educational establishment of higher education «Crimean federal university named after V. I. Vernadsky» Ministry of education and science of the Russian Federation
Russian Federation


K. A. Miroshnik
Medical academy named after S. I. Georgievskiy, the Federal state autonomous educational establishment of higher education «Crimean federal university named after V. I. Vernadsky» Ministry of education and science of the Russian Federation
Russian Federation


References

1. Самохвалова Н. А., Романчишен А. Ф., Герасимчук Р. П. и др. Вторичный гиперпаратиреоз: частота, клинические проявления, лечение // Вестник хирургии. - 2007. - № 5. - С. 78-81.

2. https://www. nice. org. uk/guidance/TA117/chapter/ 1-Guidance

3. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease // Am. j. kidney. dis. -2003. - Vol. 42. Suppl. 3. - Р. 1-201.

4. Kazuo I., Reiki I. Tc-99m-MIBI scintigraphy for recurrent hyperparathyroidism after total parathyroidectomy with autograft // Annals of nuclear medicine. - 2003. - Vol. 17. № 4. - Р. 315-320.

5. Kostakis A., Vaiopoulos G., Kostantopoulos K. et al. Parathyroidectomy in the treatment of secondary hyperparathyroidism in chronic renal failure // Int. surg. - 1997. -Vol. 82. - P. 85-86.

6. Lomonte C., Antonelli M., Losurdo N. et al. Cinacalcet is effective in relapses of secondary hyperparathyroidism after parathyroidectomy // Nephrol. dial. transplant. - 2007. -Vol. 22. - P. 2056-2062.

7. National kidney foundation. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease // Am. j. kidney. dis. - 2003. - Vol. 42. - P. 1-202.

8. Schneider R., Kolios G., Koch B. M. et al. An economic comparison of surgical and medical therapy in patients with secondary hyperparathyroidism - the German perspective // Surgery. - 2010. - Vol. 148. - P. 1091-1099.

9. Shen W. T, Kebebew E., Suh I. et al. Two hundred and two consecutive operations for secondary hyperparathyroidism: has medical management changed the profiles of patients requiring parathyroidectomy? // Surgery. - 2009. - Vol. 146. № 2. -P. 296-299.

10. Silverberg S. J., Rubin M. R., Faiman C. et al. Cinacalcet hydrochloride reduces the serum calcium concentration in inoperable parathyroid carcinoma // J. clin. endocrinol. metab. -2007. - Vol. 92. - P. 3803-3808.

11. Susan C. Pitt, Rebecca S. Sippel, Herbert Chen. Secondary and tertiary hyperparathyroidism, state of the art surgical management // Surg. clin. north. am. - 2009. - Vol. 89. № 5. - P. 1227-1239.

12. Thomas W. T. Ho, Todd P. McMullen. Secondary hyperparathyroidism presenting with vocal cord paralysis // World journal of endocrine surgery. - 2011. - № 3. - P. 122-124.

13. Tolga Özmen, Manuk Manukyan, Semiha Sen et al. Is three-gland-or-less parathyroidectomy a clinical failure for secondary hyperparathyroidism? // Turkish journal of surgery. -2014. - Cilt30. - Sayi4. - Sayfa: 201-206 / DOI: 10. 5152/UCD. 2014. 2154.

14. Tominaga Y., Matsuoka S., Uno N., Sato T. Parathyroidectomy for secondary hyperparathyroidism in the era of calcimimetics // Ther. apher. dial. - 2008. - Vol. 12. Suppl. 1. - Р. 21-26.

15. Wissam Saliba, Boutros El-Haddad. Secondary hyperparathyroidism: pathophysiology and treatment // JABFM. -September-october. 2009. - Vol. 22. № 5. - Р. 574-581.

16. Yoshihiro tominaga current status of parathyroidectomy for secondary hyperparathyroidism in Japan // NDT. - 2008. -Vol. 1. Suppl. 3. - P. 35-38.


Review

For citations:


Mykhaylichenko V.Yu., Karakursakov N.E., Miroshnik K.A. Aspects of the surgical treatment of secondary hyperparathyroidism in patients with chronic renal failure are on dialysis replacement therapy program. Kuban Scientific Medical Bulletin. 2016;(1):95-98. (In Russ.)

Views: 295


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1608-6228 (Print)
ISSN 2541-9544 (Online)