TYPICAL AND ATYPICAL FORMS OF CELIAC DESEASE: DIFFICULTIES IN THE DIAGNOSIS
https://doi.org/10.25207/1608-6228-2018-25-1-189-194
Abstract
The review analyzes materials devoted to the study of various forms of celiac disease. Particular attention is paid to the systematization of clinical manifestations and features of diagnosis of atypical forms of celiac disease. Data are given on the incidence and mechanisms of progression of disorders in the combination of celiac disease and a number of autoimmune diseases, including type 1 diabetes mellitus. This literature review promotes a better understanding of the problem of celiac disease by specialists, which will improve early diagnosis and determine the rational tactics of managing patients with different forms of the disease.
About the Authors
N. V. PORODENKO
Department of the hospital therapy, Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation.
Russian Federation
Sedina str., 4, Krasnodar, 350063.
Russian Federation
Sedina str., 4, Krasnodar, 350063.
V. V. SKIBITSKIY
Department of the hospital therapy, Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation.
Russian Federation
Sedina str., 4, Krasnodar, 350063.
Russian Federation
Sedina str., 4, Krasnodar, 350063.
V. V. ZAPEVINA
Department of the hospital therapy, Federal state budgetary educational institution for higher education “Kuban state medical university” of the Ministry of health care of the Russian Federation.
Russian Federation
Sedina str., 4, Krasnodar, 350063.
Russian Federation
Sedina str., 4, Krasnodar, 350063.
M. V. SKIBITSKAYA
Municipal budgetary healthcare institution City hospital №3.
Russian Federation
Russian Federation
Stavropolskaya str., 142, Krasnodar, 350001.
References
1. Всероссийский консенсус по диагностике и лечению целиакии у детей и взрослых. Consilium Medicum. Педиатрия. (Прил.) 2016; 1: 6-19. [All-Russian Consensus on Diagnosis and Treatment of Celiac Disease in Children and Adults. Consilium Medicum. Pediatric. 2016; 1: 6-19].
2. Орешко Л.С. Исторические и клинические аспекты целиакии. СПб., 2011. 108 с. [Oreshko L.S. Historical and clinical aspects of celiac disease. SPb., 2011. 108 р. (In Russ.)].
3. Бельмер С.В. Эпидемиология целиакии: факты и выводы. Лечащий врач. 2013; 1: 16-19. [Belmer S.V. Epidemiology of celiakia: facts and conclusions. Lechaschii Vrach Journal. 2013; 1: 16-19. (In Russ.)].
4. Catassi C., Kryszak D., Bhatti B.et al. Natural history of celiac disease autoimmunity in a USA cohort followed since 1974. Ann. Med. 2010; 42: 530-538.
5. Парфенов А.И. Целиакия. Эволюция представлений о распространенности, клинических проявлениях и значимости этиотропной терапии. М.: Анахарсис; 2007. 376 с. [Parfenov A.I. Celiac disease. Evolution of the notions of prevalence, clinical manifestations and the importance of etiotropic therapy. M.: Anakcharsis; 2007. 376 р. (In Russ.)].
6. Serena G., Camhi S., Sturgeon C. et al. The role of gluten in celiac desease and type 1 diabets. Nutrients. 2015; 7: 7143-7162.
7. Kupfer S.S., Jabri B. Celiac Disease Pathophysiology. Gastrointest. Endosc. Clin. N. Am. 2012; 22: 639-660.
8. Narula P., Porter L., Langton J. et al. Gastrointestinal symptoms in children with type 1 diabetes screened for celiac disease. Pediatrics. 2009; 124(3): 489-95.
9. Орешко Л.С. Целиакия взрослых: особенности патогенеза, клинических проявлений, диагностики, лечения и профилактики осложнений: дис. … д-ра мед. наук: 14.00.47. СПб., 2008. 291 с. [Oreshko L.S. Celiac disease in adults: features of pathogenesis, clinical manifestations, diagnosis, treatment and prevention of complications. Diss. dokt. med. nauk. Sankt-Peterburg, 2008.
10. Kelly C.P., Bai J.C., Liu E., Leffler D.A. Advances in diagnosis and management of celiac disease. Gastroenterology. 2015; 148: 1175-1186.
11. Admou B., Essaadouni L., Krati K., Zaher K. et al. Atypical Celiac Disease: From Recognizing to Managing. Gastroenterology Research and Practice. Volume 2012 (2012), Article ID 637187, 9 pages. http://dx.doi.org/10.1155/2012/637187.
12. Лазебник Л.Б., Ткаченко Е.И., Орешко Л.С., Ситкин С.И. и соавт. Рекомендации по диагностике и лечению целиакии взрослых. Экспериментальная и клиническая гастроэнтерология. 2015; 117(5): 3-12. [Lazebnik L.B., Tkachenko Ye.I., Oreshko L.S., Sitkin S.I. et al. Guidelines for diagnosis and treatment of celiac disease. Eksperimental’naya i Klinicheskaya Gastroenterologiya. 2015; 117(5): 3-12.
13. Cellier C., Grosdidier E. Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. Lancet. 2000; 356: 203-208.
14. Marietta E. A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice. J. Clin. Invest. 2004; 114: 1090-1097.
15. Сабельникова Е.А. Глютенчувствительная целиакия: распространенность в группах риска, клинические формы, лечение и диспансерное наблюдение: автореф. дис. … д-ра мед. наук. М., 2008. 39 с. [Sabelnikova E.A. (2008) Gluten-sensitive celiac disease: prevalence in risk groups, clinical forms, treatment and dispensary observation. Avtopef. diss. dokt. med. nauk. Moscow, 2008. 39 p.].
16. Mäki M., Kaukinen K. Associated Disorders in Coeliac Disease. Tamper, 1998. 89-91.
17. Smyth D.J., Vincent P., Neil M. Walker et al. Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease. N Engl J Med. 2008; 359: 2767-2777.
18. Tuomilehto, J. The emerging global epidemic of type 1 diabetes. Curr. Diab. Rep. 2013; 13: 795-804.
19. De Goffau M.C., Fuentes S., van den Bogert B. et al. Aberrant gut microbiota composition at the onset of type 1 diabetes in young children. Diabetologia. 2014; 57: 1569-1577.
20. Mojibian M., Chakir H., Lefebvre D.E. et al. Diabetes-specific HLA-DR-restricted proinflammatory T-cell response to wheat polypeptides in tissue transglutaminase antibody-negative patients with type 1 diabetes. Diabetes. 2009; 58: 1789-1796.
21. Warncke K.; Liptay S.; Frohlich-Reiterer E. et al. Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: Results from the DPV initiative. Pediatr. Diabetes. 2016; 17(3): 191-8.
Review
For citations:
PORODENKO N.V., SKIBITSKIY V.V., ZAPEVINA V.V., SKIBITSKAYA M.V. TYPICAL AND ATYPICAL FORMS OF CELIAC DESEASE: DIFFICULTIES IN THE DIAGNOSIS. Kuban Scientific Medical Bulletin. 2018;25(1):189-194. (In Russ.) https://doi.org/10.25207/1608-6228-2018-25-1-189-194
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