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State of free radical oxidation in the surgical treatment of vitreous floating opacities

Abstract

The paper describes the development of the local and general statement of free radical oxidation in patients with vitreous opacities during vitrectomy. We examined 35 patients who underwent surgical treatment of vitreous opacities. We observed a positive dynamics of free radical oxidation after the operation: a full recovery of biochemical parameters in the late postoperative period. Among the complications mentioned cataract development in some patients who did not receive antioxidant therapy. Vitrectomy improves the visual function and is supposed to be safe and efficient in patients with floating vitreous opacities.

About the Authors

A. V. Malyshev
GBUZ Krasnodar regional clinical hospital № 1 prof. Ochapovsky ministry of health of the Krasnodar territory
Russian Federation


V. N. Trubilin
GBUZ Krasnodar regional clinical hospital № 1 prof. Ochapovsky ministry of health of the Krasnodar territory
Russian Federation


S. M. Makkaeva
GBUZ Krasnodar regional clinical hospital № 1 prof. Ochapovsky ministry of health of the Krasnodar territory
Russian Federation


S. V. Janchenko
GBUZ Krasnodar regional clinical hospital № 1 prof. Ochapovsky ministry of health of the Krasnodar territory
Russian Federation


Z. Zh. Alrashid
GBUZ Krasnodar regional clinical hospital № 1 prof. Ochapovsky ministry of health of the Krasnodar territory
Russian Federation


Y. A. Gusev
GBUZ Krasnodar regional clinical hospital № 1 prof. Ochapovsky ministry of health of the Krasnodar territory
Russian Federation


L. Sh. Ramazanova
GBUZ Krasnodar regional clinical hospital № 1 prof. Ochapovsky ministry of health of the Krasnodar territory
Russian Federation


References

1. Арчаков А.И., Девиченский В.М., Карузина И.И., Ивков Н.Н., Александрова Т.А., Доронин П.П., Сорокина М.М. Влияние концентрации буфера на скорость реакций электронного переноса в микросомах печени // Биохимия. - 1968. - Т. 33. -С. 479.

2. Теселкин Ю.О., Бабенкова И.В., Любитский О.В., Клебанов Г.И., Владимиров Ю.А. Измерение антиоксидантной активности сыворотки крови с помощью системы «гемоглобин -перекись водорода - люминол» // Вопросы медицинской химии. -1998. - Т. 44 (1). - С. 70-76.

3. Bishop P.N. Structural macromolecules and supramolecular organisation of the vitreous gel // Prog. retin. eye. res. - 2000. May. -№ 19 (3). - Р. 323-344.

4. Deguine V., Menasche M., Ferrari P., Fraisse L., Pouliquen Y., Robert L. Free radical depolymerization of hyaluronan by Maillard reaction products: role in liquefaction of aging vitreous // Int. j. biol. macromol. -1998. Feb. - № 22 (1). Р. 17-22.

5. Hofmann H., Schmut O. The inability of superoxide dismutase to inhibit the depolymerization of hyaluronic acid by ferrous ions and ascorbate // Albrecht. von. graefes. arch. klin. exp. ophthalmol. -1980. - № 214 (3). - Р. 181-185.

6. Оrganisciak D.T., Noell W.K. Hereditary retinal dystrophy in the rat: lipid composition of debris // Experimental. eye. research. -1976. - V. 22 (2) - Р. 101-113.

7. Schulz-Key S., Carlsson J.O., Crafoord S. Longterm follow-up of pars plana vitrectomy for vitreous floaters: complications, outcomes and patient satisfaction // Acta. ophthalmol. - 2011. Mar. - № 89 (2). -Р. 159-165.

8. Sun Y., Oberley L.W., Li Y. A simple method for clinical assay of superoxide dismutase // Clin. chem. - 1988. - V. 34. -Р. 497-500.

9. Ueno N. Changes in vitreous structure caused by oxygen free radicals. Nihon ganka gakkai zasshi. - 1995. Dec. - № 99 (12). -Р. 1342-1360.


Review

For citations:


Malyshev A.V., Trubilin V.N., Makkaeva S.M., Janchenko S.V., Alrashid Z.Zh., Gusev Y.A., Ramazanova L.Sh. State of free radical oxidation in the surgical treatment of vitreous floating opacities. Kuban Scientific Medical Bulletin. 2014;(2):82-86. (In Russ.)

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ISSN 1608-6228 (Print)
ISSN 2541-9544 (Online)