ESTIMATION OF CLINICAL AND PHARMACOECONOMIC EFFICIENCY OF PROTON PUMP INHIBITORS DURING GASTROESOPHAGEAL REFLUX DISEASE (GERD) TREATMENT
https://doi.org/10.25207/1608-6228-2018-25-6-160-163
Abstract
Aim. The study was conducted to estimate the clinical and pharmacoeconomic efficiency of proton pump inhibitors (PPIs) omeprazole and esomeprazole when GERD patients undergo a course of medical treatment.
Materials and methods. 25 GERD patients with a history of the disease for more than 5 years were under observation in Krasnodar regional clinical hospital № 2 from 2017 till 2018. All the patients have been thoroughly examined. Conservative therapy included the «gold standard» of proton pump inhibitors. Evaluation of the efficiency included the number of disease relapses in the period of dynamic observation and the calculation of the cost-effectiveness ratio.
Results. When patients were taking esomeprazole, the relapses of the GERD disease were rare. The cost-effectiveness ratio was lower.
Conclusion. The use of esomeprazole during the treatment of GERD patients has lower economic expenditures. The relapses of the disease are also less frequent.
About the Authors
N. E. ShabanovaRussian Federation
Krasnykh Partizan str., Krasnodar, Russia, 350012; Sedina str., 4, Krasnodar, Russia, 350063.
N. V. Korochanskaya
Russian Federation
Krasnykh Partizan str., Krasnodar, Russia, 350012; Sedina str., 4, Krasnodar, Russia, 350063.
A. I. Ponomareva
Russian Federation
Krasnykh Partizan str., Krasnodar, Russia, 350012; Sedina str., 4, Krasnodar, Russia, 350063.
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Review
For citations:
Shabanova N.E., Korochanskaya N.V., Ponomareva A.I. ESTIMATION OF CLINICAL AND PHARMACOECONOMIC EFFICIENCY OF PROTON PUMP INHIBITORS DURING GASTROESOPHAGEAL REFLUX DISEASE (GERD) TREATMENT. Kuban Scientific Medical Bulletin. 2018;25(6):160-163. https://doi.org/10.25207/1608-6228-2018-25-6-160-163
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