THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A Literature Review) PART I. MODERN VIEWS ON THE EMCV STRUCTURE AND ITS VIRAL CYCLE
https://doi.org/10.25207/1608-6228-2019-26-2-214-223
Abstract
There have been a growing number of the outbreaks of human diseases with typical zoonotic infections, which have previously occurred exclusively in veterinary practice. Among them is monkeypox, whose first occurrence outside the African continent was registered in the USA in the spring of 2003. An important factor contributing to the penetration of infections into the human population is a close contact of people with fauna representatives in the context of intensively growing cities. Therefore, research into new zoonotic diseases, which are potentially dangerous to humans, seems to be critically important. Thus, retrospective studies carried out among the Peru population in 2009 revealed the cases of the encephalomyocarditis virus (EMCV) (Picornaviridae family, Cardiovirus genus) infection in people having suffered from acute febrile illness. A new virus strain belonging to the same genus was described during the infection outbreak among primates of the Sukhumi Monkey nursery (Republic of Abkhazia) in 1990–1999. This strain was also identified during the outbreak among the monkeys of the Primatological Centre in the Krasnodar Krai in 2012. In this review, we generalize the data available on the structure, virulence factors and distribution of EMCV.
About the Authors
Akop A. Kalajdzhjan
Scientific Research Institute of Medical Primatology
Russian Federation
Russian Federation
PhD Researcher, Laboratory of Molecular Biology,
Mira str., 177, Sochi, 354376
Azamat Kh. Kade
Kuban State Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Dr. Sci. (Med.), Prof., Head of Department, Department of General and Clinical Pathological Physiology,
Mitrofanа Sedinа str., 4, Krasnodar, 350063
Pavel P. Polyakov
Kuban State Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Research Assistant, Department of General and Clinical Pathological Physiology,
Mitrofanа Sedinа str., 4, Krasnodar, 350063
Alla A. Gudmanova
Krasnodar City Clinical Hospital No. 3, Ministry of Healthcare of Krasnodar Krai
Russian Federation
Russian Federation
Physician,
Aivazovskogo str., 97, Krasnodar, 350040
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Review
For citations:
Kalajdzhjan A.A., Kade A.Kh., Polyakov P.P., Gudmanova A.A. THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A Literature Review) PART I. MODERN VIEWS ON THE EMCV STRUCTURE AND ITS VIRAL CYCLE. Kuban Scientific Medical Bulletin. 2019;26(2):214-223. (In Russ.) https://doi.org/10.25207/1608-6228-2019-26-2-214-223
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