Preview

Kuban Scientific Medical Bulletin

Advanced search

Comparative estimation of maternal and fetal thrombophilia in patients with early (under 34 weeks of gestation) and late forms of pre-eclampsia

Abstract

The article presents the results of the comparative analysis of maternal and fetal thrombophilia in patients with early (under 34 weeks of gestation) and late forms of pre-eclampsia. The diagnosing of latent acquired and genetic thrombophilia in women of high risk groups makes possible to predict the risk of pre-eclampsia and to substantiate the prophylaxis of complicated pregnancy. Such prophylaxis reduces the rate and the heaviness of pre-eclampsia and the number of perinatal complications.

About the Author

M. D. Andreeva
Kuban state medical university
Russian Federation


References

1. Макацария А.Д., Бицадзе В.О., Акиньшина С.В. Синдром системного воспалительного ответа в акушерской практике. - М.: МИА, 2006. - 442 с.

2. Шифман Е.М. Преэклампсия, HELLP-синдром. - Петрозаводск: Ител-тек, 2002. - С. 432.

3. Blake G.J., Ridker P.M. Novel clinical markers of vascular wall inflammation // Circ. res. - 2001. - № 89. - Р. 763-771

4. Davison J.M., Homuth V., Jeyabalan A. et al. New aspects in the pathophysiology of preeclampsia // J. am. soc. nephrol. -2004. - Vol. 15. - P. 2440-2448.

5. Brosens I., Pijnenborg R., Vercruysse L. et al. The «Great obstetrical syndromes» are associated with disorders of deep placentation // Amer. j. obstet. gynecol. - 2011. - V. 2004 (3). -P. 193-201.

6. Hale S.A., Badger G.J., McBride C.M. et al. Pregnancy vascular dysfunction in women who subsequently develop hypertension during pregnancy. Pregnancy hypertension // Int. j. womens cardiovasc. health. - 2013. - V. 3. - P. 140-145.

7. Huppertz B. Placental origins of preeclampsia: challenging the current hypothesis // Hypertension. - 2008. - V. 51 (4). - P. 970-975.

8. Malek-Khosravi S., Kaboudi M. et al. Plasma homocysteine in preeclampsia. Pregnancy hypertension // Int. J. womens cardiovasc. health. - 2009. - V. 28. - P. 13-22.

9. Pijnenborg R., Vercruysse L., Hanssens M., Brosens I. Endovascular trophoblast and preeclampsia: A reassessment // Pregnancy hypertension: an international journal of women's cardiovascular health. - 2011. - January. V. 1. Issue 1. - P. 66-71.

10. Roberts J. Preeclampsia a two-stage disorder: what is the linkage? Are there directed fetal/placental signals? // In: Lyall, Belfort M., editors. Preeclampsia: etiology and clinical practice. - United Kingdom: Cambridge university press, 2007. - P. 183-194.

11. Rodger M.A. An update on thrombophilia and placenta mediated pregnancy complications: What should we tell our patients? // Thromb. res. - 2013. - V. 131 (1). - P. 25-27.


Review

For citations:


Andreeva M.D. Comparative estimation of maternal and fetal thrombophilia in patients with early (under 34 weeks of gestation) and late forms of pre-eclampsia. Kuban Scientific Medical Bulletin. 2015;(2):10-14. (In Russ.)

Views: 199


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1608-6228 (Print)
ISSN 2541-9544 (Online)