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Drug therapy efficacy for the syndrome of chronic pelvic pain relapses in perinatal endometriosis

Abstract

Comparative analysis of drug therapy efficacy for the syndrome of chronic pelvic pain relapses in perinatal endometriosis has been presented: it included dienogest monotherapy and combined interleukin-2 (il-2) and dienogest therapy. It has been proved that dienogest in combination with Interleukin-2 (ronkoleukin) followed by supportive therapy with dienogest-containing oral contraceptives (DCOK) is more effective for arresting pain syndrome, eliminating psycho-emotional disorders and preventing relapses.

About the Authors

R. A. Musolyants
Kuban state medical university of the Ministry of health care of the Russian Federation
Russian Federation


I. I. Kutsenko
Kuban state medical university of the Ministry of health care of the Russian Federation
Russian Federation


E. I. Kravtsova
Kuban state medical university of the Ministry of health care of the Russian Federation
Russian Federation


N. R. Danilova
Kuban state medical university of the Ministry of health care of the Russian Federation
Russian Federation


References

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2. Сельков С.А., Егорова В.Н. Клинический опыт применения ронколейкина (рекомбинантного интерлейкина-2) в гинекологии: Пособие для врачей. - СПб, 2010. - С. 32.

3. Чернуха Г.Е. Хроническая тазовая боль: причины и последствия // Проблемы репродукции. - 2011. - № 5. -С. 83-89.

4. Колесникова Н.В., Куценко И.И., Хорольская А.Е., Мусольянц Р.А. Особенности продукции цитокинов у пациенток с хронической тазовой болью, ассоциированной с перитонеальным эндометриозом // Российский иммунологический журнал. - 2015. - Т. 9 (18). № 1. - С. 108.

5. Flor H., Turk D. C. eds. Chronic pain: An integrated biobehavioral approach. - London: Informa healthcare publishing group. - 2011.


Review

For citations:


Musolyants R.A., Kutsenko I.I., Kravtsova E.I., Danilova N.R. Drug therapy efficacy for the syndrome of chronic pelvic pain relapses in perinatal endometriosis. Kuban Scientific Medical Bulletin. 2015;(6):89-93. (In Russ.)

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ISSN 1608-6228 (Print)
ISSN 2541-9544 (Online)