The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children
Abstract
Helicobacter pylori (H. pylori) is a key factor in the etiology of various gastrointestinal diseases. The interaction analysis of a pathogenicity factor of H. pylori dupA and morphological changes in the gastric mucosa (GM) in children with chronic inflammatory diseases of the upper gastrointestinal tract (GIT). The results show the influence of this factor on the pathogenicity on the severity of clinical disease. I n this study the dependence of the formation of gastritis high degree of activity, and the incidence of sclerotic and dystrophic changes in the coolant depending on the carrier dupA gene have been identified. However, the presence of dupA gene was associated with a low chance of developing atrophy.
About the Authors
E. V. Dudnikova
State educational Institute of high professional training «The Rostov state medical university»
Russian Federation
Russian Federation
E. V. Gilis
State educational Institute of high professional training «The Rostov state medical university»
Russian Federation
Russian Federation
V. G. Zaz'yan
State educational Institute of high professional training «The Rostov state medical university»
Russian Federation
Russian Federation
A. V. Zaz'yan
State educational Institute of high professional training «The Rostov state medical university»
Russian Federation
Russian Federation
M. S. Chernova
State educational Institute of high professional training «The Rostov state medical university»
Russian Federation
Russian Federation
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Review
For citations:
Dudnikova E.V., Gilis E.V., Zaz'yan V.G., Zaz'yan A.V., Chernova M.S. The influence of the factor of pathogenicity of Helicobacter pylori dupa on the nature of the morphological picture of gastric mucosa in diseases of the upper gastrointestinal tract in children. Kuban Scientific Medical Bulletin. 2016;(3):59-62. (In Russ.)
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