DIFFUSE MENINGEAL MELANOMATOSIS OF THE CENTRAL NERVOUS SYSTEM
Abstract
We report a case of primary diffuse meningeal melanomatosis, a rare variant of primary malignant melanoma of the CNS, in a 25-year-old woman. The disease was clinically manifested with obstructive hydrocephalus and severe polyneuritis of cranial and spinal nerves. The results of the CSF cytology and biopsy of the meninges were negative. There was a steady progression of the disease despite the success of the ventriculoatrial shunt. The disease was diagnosed only at autopsy.
About the Authors
G. A. Gerasimenko
GBOU VPO Kuban state medical univercity
Russian Federation
Russian Federation
L. V. Shagal
GBOU VPO Kuban state medical univercity
Russian Federation
Russian Federation
M. A. Barabanova
GBOU VPO Kuban state medical univercity
Russian Federation
Russian Federation
N. V. Zabolotskyh
GBOU VPO Kuban state medical univercity
Russian Federation
Russian Federation
I. S. Blumenau
GBUZ Krasnodar regional hospital № 1 named by professor S. V. Ochapovsky
Russian Federation
Russian Federation
References
1. Улитин А. Ю., Олюшин В. Е., Сафаров Б. И., Мацко Д. Е. Метастатические опухоли головного мозга. - СПб, 2010. - 384 с.
2. Avril M. F., Cascinelli N., Cristofolini M. Clinical diagnosis of melanoma: - W. H. O. Melanoma programme publications. - Milano (Italy), 1994. - № 3.-28 p.
3. Chamberlain M. C. Neoplastic meningitis // Neurologist. - 006. - Vol. 12. № 4. - P. 179-187.
4. Dupuis F., Sigal R., Margulis A. et al. Cerebral magnetic resonance imaging (MRI) in diagnosis of leptomeningeal carcinomatosis in melanoma patients // An. Dermatol. venereal. - 2000. - Vol. 127. № 1. - P. 29-32.
5. Patchell R. A. The management of brain metastases. - Cancer treat rev. - 2003. - Vol. 29. - P. 533 - 540.
6. Sawaya R., Bindal R., Lang F. et al. Metastatic tumors // Brain tumors: An Enciclopedic Approach / Ed. by A. H. Kaye, E. R. Jr.Laws. - New York: Churchill Livingston, 2001. - P. 999-1026.
Review
For citations:
Gerasimenko G.A., Shagal L.V., Barabanova M.A., Zabolotskyh N.V., Blumenau I.S. DIFFUSE MENINGEAL MELANOMATOSIS OF THE CENTRAL NERVOUS SYSTEM. Kuban Scientific Medical Bulletin. 2014;(1):196-198. (In Russ.)
Views:
610
Email this article 