It was performed the literature data analysis on the mechanisms of cerebral palsy (CP). Presents current information about the processes of the brain differentiation considered the pathogenesis of lesions that underlie the clinical manifestations of the CP. Understanding the processes intensively in the central nervous system is essential for the early diagnosis of disease among children in this age group received to date data indicate that the major activities for the early diagnosis and early treatment of perinatal pathological changes should be carried out in the prenatal period and during the first year a child's life.

The high-frequency electric field in the cervical vagus nerve of cats in a state of surface anesthesia, along with a luminous background observed 3 hearth glow associated with the ECG. This one was afferent, the largest in area and the spread of high speed in the direction of the heart to the brain, the other two efferent, smaller in size and a low rate of spread of the brain to the heart.

The article presents the results of a study of 155 root canals of molars removed the upper and lower jaws, of whom 620 made of thin sections for scanning electron microscopy studies. As the results of the study, an increase in the curvature of the root canals of molars in the bucco-lingual and mediodistal directions by more than 25°, significantly reduces the quality of the tooling. Taking into account individual features of architectonic root canals, endodontic instruments expand the range and improve its cutting efficiency will ensure higher quality tooling.

Metastatic brain and spine when kidney cancer is one of the leading places. Surgical treatment with subsequent targeted therapy did not significantly improve the lifetime and the duration of DFS in this group of patients. A comparative study of simultaneous operated patients clear cell carcinoma kidney cancer with subsequent targeted therapy Nexavar and patients operated two-stage, with removal of the primary lesion, then - metastatic and subsequent targeted therapy has shown the feasibility of simultaneous operations. The life expectancy of patients, simultaneous operated above. However, a significant increase is not marked, that makes us keep looking for new ways to solve the problem

The purpose of research is to conduct a retrospective analysis of the prevalence and incidence of myopia in the Krasnodar region in the different age groups. This paper analyzes the statistics of the annual reports of health care institutions from 2000 to 2012 inclusive.

Purpose - to estimate the effect of the order of the Ministry of health of the Russian Federation of december 15, 2009 № 991n. the level of mortality of patients with associated trauma in Adygei Republican Clinical Hospital (ARCB) before and after its implementation. After the implementation of this order affected mortality decreased from 14.6% to 10.1%. There are several negative aspects that must be considered in the future of medical care with associated trauma.

In a study of 2239 patients the diagnosis of sick sinus syndrome was made in 120 children aged from 7 to 17 years of both sexes. According to the results of the cardiorespiratory synchronism test and to clinical methods that exclude organic heart disease, there were identified 103 patients with sick sinus syndrome of functional nature among 120 children. It is shown that the establishment of functional or organic nature of sick sinus syndrome by the integrative objective screening method - the cardiorespiratory synchronism test, as compared to conventional diagnostic methods is fast, less complexity. Diagnosis by the use of a functional test is carried out in children with different types of personality, anxiety levels, adaptability, ECG-variants. The significance of the cardiorespiratory synchronism test in the evaluating of the efficacy of treatment in children with sick sinus syndrome is shown.

This study is aimed at identifying risk factors for retrochorial hematoma (RHG) in pregnant women in the I trimester. The study involved 188 patients. The study group included 115 pregnant women with RHG in terms of 6 to 12 weeks (group I). The control group (II group) were 73 apparently healthy pregnant women (no RHG). We have analyzed the factors of age and obstetric history, which resulted in the formation of a link between the presence of RHG and previous obstetric history early losses in history, scraping the uterine cavity about the artificial surgical, spontaneous abortions and developing pregnancy, cesarean section.

Cases with mesognathic dental arches present microdontia, normodontia (normal teeth sizes), and macrodontia. As a rule, odontometric parameters do not depend on gender or racial features as much as they do on the dentition type. Regardless of the absolute indicators, the relative indicators and index values are relatively stable, being to a lesser extent determined by the size of the teeth, and define whether the sizes of the teeth match the parameters of the dental arches. There is evidence that identification of internal links between any components related to the structural and functional status of the organism rate among the most long-run objectives in medical anthropology.

The studies of influence all the phases of uveoscleral outflow stimulation on the intraocular pressure (IOP) level were carried out in the course of 37 glaucomatous operation. Two methodics of glaucomatous surgery and two viscoelastics with different pseudoplasticity were compared. The IOP measurement was carried out intraoperatively and 24 hours later. It was stated that posterior sclerectomy was accompanied by IOP decrease on 4,0±0,5 mm Hg (p<0,05). The sclera profound flap and the external schlemm's channel wall cutout also decrease IOP on 4,2±0,5 mm Hg. Although the shunt implantation into the anterior chamber decreases IOP considerably, the safest level is achieved with suprauveal space activation and use of viscoelastic with higher level of pseudoplascticity.

Character of the central nervous system functions damage influences a feature of generation visual generated potential (VGAP) components by children with neurosensory bradyacuasia (NSB). The configurations of early and late reductants of the VGAP differ for hard of hearing and healthy children. At NSB the amplitude of negative reductant is reduced in frontal, temporal and occipital regions of both brain hemispheres as contrasted to by control. The decrease of amplitude of VGAP positive reductants are connected to failure the hard of hearing children attention function.

Article presents the results of the treatment of complicated forms of colon cancer in patients with elderly using laparoscopic technology. The authors analyzed the data and showed the effectiveness of minimally invasive technologies in treatment of colon cancer.

The aim of the research was to study the characteristics of heart rate variability (HRV) criteria to detect early vegetative imbalance in young people with overweight and obesity. From 163 students with an average age of 22,2 years were conducted to study the quality of life, аnthropometry, bioimpedance test, HRV at 10-minute intervals. In the normal range of integral indicator HRV - tension index (TI) - with rising TI grew sympathetic activation and decreased the overall HRV and parasympathetic activity. Young people with increased visceral fat recorded higher values in systolic and diastolic blood pressure and TI. The level of visceral fat has determinating effect on the sympatho-vagal balance, modulation which reliably reflects indicator HRV - TI.

The analysis of ultrasound studies of 98 patients with cervical cancer II-III stage before treatment and after a course of chemo-radiotherapy (CRT). Found changes in cervix in gray-scale. The use of Doppler in the study of intratumoral blood flow possible to determine increasing index resistance (IR) in 47 women with good outcome treatment of the disease (criterion Wilcoxon, p < 0.05) after a course of CRT. Remained abnormal blood flow (IR = 0.2-0.46) in 51 women with bad outcome treatment of the disease. To evaluate the effectiveness of the CRT of cervical cancer should be used Doppler.

The research outcomes suggest certain dependence between the major linear parameters of the mesognathic dental arches and the permanent teeth sizes. Individuals with macrodontia had dental arches that were significantly wider and deeper compared to cases with microdontia. As a rule, the major parameters of the dental arches are determined by the size of the permanent teeth and, to a smaller extent, by gender or racial features.

Based on the information-structural theories of pain and clinical and physiological studies have examined the pathogenesis of chronic stomalgia, selected clinical and pathogenetic variants of chronic stomalgia: somatogenic (nociceptive), neurogenic (neuropathic), and psychogenic disregulation and integrative.

The paper presents the results of a clinical study of primary medical documents dental clinic 8470 people (3613 men and 4857 women) aged 22 to 93 years in order to study the causes of the removal of natural teeth. Patients who had teeth removed 10 597, for various reasons, were divided by age and sex. Established age particularly the loss of teeth, which are not dependent on gender. During one visit to the dentist-surgeon people elderly are removed, respectively, 1.31 and 1.95 of the tooth. Information relevant to the organizers of dental care, dentists and specialists in gerontology and geriatrics.

The patients with Ischemic heart disease (IHD) who were ill since a few months till a few years have been checked-up. Fifty one patient suffering from IHD who were dispensary polyclinic treated have been medically examined. Among the examined patients there were 32 ill people with stenocardia tension of the 1st and 2 nd functional classes, 3 persons with unstable stenocardia, 11 patients with auricular fibrillation, 3 patients were with ventricular premature beats and tachycardia, atrioventricular blocks of the 3rd degree were also found in 2 patients. The majority of ill people were revealed as cardiac failure patients of 2A stage - 35 patients, as well as arterial hypertension of the 3rd stage in 44 people.Body mass index (BMI) was more than 30 kg/m². An average age of ill people was 65 years. The condition of carbohydrate exchange in the people who were ill was controlled by way of determining the HbAlc by immunochemical method and the level of an empty stomach glucose plasm - by glucose oxidase way. It has been found out that an average level of blood glucose came up to 6,24±0,27 mmol/l. In this case an average value of glycated haemoglobin was registered as 5,95± 0,21%. An average value as for body weight Index was 30,07±4,15 kg/m².The majority of the people madically checked had the level of low thickness lipoproteins higher than 2,6 mmol/l (100 mg/dl). Seventeen medically checked people manifested the level of high thickness lipoproteins that was more than 1.3 mmol/l (50 mg/dl). Sixteen patients had triglyceride level more than 1.7 mmol/l (150 mg/dl). Eight people out of fifteen checked up manifested an increased level of C-reactive albumen.The level of blood glucose and glycated haemoglobin was correlated with the level of aspartate transaminose. Alterations in the content of common cholesterol of blood serum for the value of 52,9%, triglycerides- for the value of 17,2% depended upon the alterations in the content of glycated haemoglobin. The conclusion has been made that Ichemic heart disease patients reveal dominating metabolic disturbances, reflect disglycemia, dislipidemia as well as obesity and all that radically aggrivates the major diseases processes.

Changes occurring which took place in epidermis skin after injection drugs «radiesse» and «luminaire» are analyzed in the experiment. Preparations introduced endodermal evaluation results conducted at 2, 4 and 16 weeks experiment to drug «radiesse» and at 2 and 16 weeks to drug «luminaire». Slices stained hematoxylin and eosin, by Weigert and Van-Gieson for selective detection DNA used reaction Feulgen. Distribution of total protein studied in preparations stained amido - black at pH 2.2, and cationic at pH 8.2. Spended the morphometry of cores were differentiated in layers epidermis and given assessment their optical density. It is shown that the introduction of fillers lead to increase thickness epidermis more than 1.5. The zone of germenative compartment increases mitotic activity in epithelial cells. Cells of granular layer increasing temp of protein synthesis having cationic charge. Revealed changes induced status DNA cell nuclei differentiated layers epidermis.

Presents a literature review on the effectiveness of antiplatelet prophylaxis of micro- and macroangiopathies in diabetes mellitus type 2.

Disorders of hypoxic and free radical origin as they rise can lead to the destruction of cells and, consequently, often determine the fate of the organ, tissue and ultimately the whole organism. Hence, the relevance of using high-performance antihypoxants and antioxidants in individual and complex schemas, standards of disease treatment. The aim of the study was to determine the logistics of the ways of treatment and the intensity of use of drugs of etilmetilgidroksipiridina succinate for antioxidant therapy in a particular region to represent the common aspects of their application.

During the course of chronic obstructive pulmonary disease (COPD) and it's progression occurs oxidative stress (OS) is characterized as a shift of pro-/anti-oxidants in the direction of the first link. For a comprehensive evaluation of the operating system used was an integral indicator of prooksidant-/antioxidant systems - a combo of blood. A significant increase in this index during exacerbation of COPD show a sharp imbalance in the pro-/anti-oxidants. Installed opposite changes of indicators of activity of enzymes of the antioxidant protection (AOP) of red blood cells, with a sharp oppression of non-enzymatic link of AOP, which is an additional adverse factor in the functioning of the antioxidant system. Identified significant oxidative changes in patients with COPD give ground to the additional purpose of drug therapy, with strong directional antihypoxic and antioxidant effects.

The device for laser-optical diagnostics (LODdsf) in dentistry. The use LODdsf for the functional estimation of periodontal diseases is proved. Sensitivity and high information LODdsf provided an opportunity to evaluate differentiated initial preclinical stage of the inflammatory process in all topographic zones of the gums, which determined the timely assignment of corrective therapy.

It was done the analysis of interrelations between different metabolic pathways (which responsible for atrophic colpitis formation) in vagina tissue at women in post reproductive period. The results of our investigation have showed that carbohydrates' metabolism in vagina tissue at atrophic process has changed into pentose phosphate pathway activation, disturbance in end glycolytic products formation. Tri carbonic acids synthesis' velocity was inhibited was depressed in this situation. The composition of fatty acids in vaginal tissue has changed into increasing of polyunsaturated fatty acids quantity. The results of investigation gave us the possibility to deep our imagination about pathogenesis of atrophic process formation in vaginal tissue and shows that the main cause of atrophic process based on changes in cell metabolism due to affection of different enzymatic systems' working.

To reveal the interrelation between the level of the fraktalkin plasma and indicators of the dopplerechocardiography (ECHO-CS) were examined 135 patients with the arterial hypertension (AH), stenocardia tension (ST) and their combination (AH+ST). It was established the influence of the system of inflammation and giperfraktalkinemiya on the structure and a functional condition of the heart at the patients with the cardio-vascular pathology. During the isolated AH and ST there were observed interrelations of the weak force between the level of the fraktalkin and some indicators of ECHO-CS. During the combination of AH+ST there were observed the strong correlative interrelations of the level of fraktalkin with a number of the indicators of the ECHO-CS, which reflected with a condition of both the left, and the right heart sections and a condition of the pulmonary haemodynamic. So the correlative interrelation between the level of the fraktalkin and functional class of heart failure were observed.

The introduction of information technology in the work of the medical organizations of various levels is one of the urgent tasks of modernization. Constructed visuals and simulations of processes of medical examination and preventive inspections in the medical organization. The simulation results allow to estimate the costs of doctors, nurses and support staff; select the most labor-intensive processes and operations; to forecast labor in depending on expected number of adult and juvenile patients; find ways to improve the efficiency of the medical organization.

In the survey data, 37 patients suffering from inflammatory bowel disease, set a high frequency of dental pathology presented catarrhal and recurrent aphthous stomatitis, inflammatory periodontal diseases and some others. Views. Marked hemodynamic disorders of organs and tissues of the oral cavity. Established imbalance in the content of pro- and anti-inflammatory cytokines oral fluid. The high incidence of viral infections, Epstein-Barr virus in the oral mucosa.

We investigated the oxygen-dependent metabolism of polymorphonuclear leukocytes (PML) in peripheral blood of patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs) with different clinical manifestations with methods stimulated barium sulfate luminol- and lucigenin-dependent chemiluminescence. Revealed the violations of oxidative metabolism PML the blood in patients with asthmatic triad, resulting in a decrease in the total production of reactive oxygen species (ROS) and production of superoxide anion radical PML compared with healthy donors. In patients with chronic urticaria, worsening after administration of NSAIDs, significant changes in ROS production relative to such a healthy donors were not identified.