Preview

Kuban Scientific Medical Bulletin

Advanced search

OPPORTUNITIES AND PROSPECTS OF THE SYSTEM INTEGRATED ASSESSMENT OF IMMUNITY OF CHILDREN SUFFERING ULCER DUODENUM

https://doi.org/10.25207/1608-6228-2017-24-4-109-114

Abstract

Aim. To explore some regularities of the immune system and resistance in children with ulcer duodenum. On the basis of systemic pathogenetic approach to develop a system of integrated assessment of the immunity of the child with the ulcer duodenum.

Materials and methods. A clinical and immunological study of 114 children aged 5-14 years, suffering from an ulcer duodenum. The control group consisted of 30 healthy children of similar age. Investigation of venous blood were performed on the day after admission and after a course of appropriate treatment before discharge. By mathematical analysis of unsubstantiated "factor" structure of the immune system in normal and ulcer duodenum.

Results. At different stages of the disease varies the amount and structure of relations between the components within the immune system and its relationship with other systems. Conclusion. These peculiarities – a normal physiological response of the immune system to develop an immunological process in the mucosa of duodenum. 

About the Authors

A. V. Polyanskiy
GUZ «Regional Clinical Children's Hospital»
Russian Federation

Corresponding author:  Alexei V. Polyanskiy

58, 2-nd passage Shevchenko Street, Krasnodar, 350001; tel.: 8-903-4-111-340



A. V. Burlutskaya
Kuban State Medical University of the Ministry of Health Care of the Russian Federation
Russian Federation
4 Sedina Street, Krasnodar, 350063


References

1. Zemskov A.M., Zemskov V.M., Esaulenko I.E., Zemskov M.A., Thin R.V., Zlokhodov V.I. New principles of evaluation and correction of immunological disorders. – Moscow: "Triada-X", 2008. 336 p. (In Russ.).

2. Kolkhir P.V. Evidence-based allergology-immunology. – Moscow: Practical medicine, 2010. 528 p. (In Russ.).

3. Mail, D. Immunology. – Moscow, Logosfera, 2007. 568 p.

4. Zaichik A.Sh., Churilov L.P. General pathophysiology. – St. Petersburg: ELBI, 2007. 624 p. (In Russ.).

5. Novikov DK, Novikov P.D. Clinical immunopathology. Leadership. M.: Med. Lit., 2009. 464 p. (In Russ.).

6. Ross G.D. Identification of human lymphocyte subpopulations by surface marker analysis. Blood.1979; 53: 779-811.

7. Manchini G., Carbonara A., Heremans J. Immunochemical quantitation of antigens by single radial immunodiffusion. Immu¬nochemistry. 1965; 2(3): 235-254.

8. Kozlov L.V., Vavilova L.M., Golosova Т.V. The Micromethod of the Determination of Complement Factors. Immunology. 1985; 3: 66-68.

9. Venglinskaya EA, Mazhara N.F. A method for studying the phagocytic function of blood microphages in laboratory animals us¬ing the NST test. Invention and rationalization in medicine. – M., 1987. 135 p.

10. Loida Z., Goserau R., Shibler T. Histochemistry of enzymes, laboratory methods. – M., 1982. 271 p. (In Russ.).

11. Venglinskaya E.A., Rukavtsov B.I., Shubich M.G. Fluores¬cence-cytochemical detection of free cytoplasmic cationic protein in blood leukocytes. Laboratory business. 1976; 5: 270 -273.

12. Shubich M.G. Cytochemical determination of leukocyte alkaline phosphatase. Laboratory business. 1965; 6: 10-14.

13. Khachaturov E.N., Smirnova E.A. Application rivanol-SO2 for DNA cytofluorimetry. Izvetstia. ANSSSR. Series Biologi. 1966; 6: 900-905.


Review

For citations:


Polyanskiy A.V., Burlutskaya A.V. OPPORTUNITIES AND PROSPECTS OF THE SYSTEM INTEGRATED ASSESSMENT OF IMMUNITY OF CHILDREN SUFFERING ULCER DUODENUM. Kuban Scientific Medical Bulletin. 2017;(4):109-114. (In Russ.) https://doi.org/10.25207/1608-6228-2017-24-4-109-114

Views: 470


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1608-6228 (Print)
ISSN 2541-9544 (Online)