OPPORTUNITIES AND PROSPECTS OF THE SYSTEM INTEGRATED ASSESSMENT OF IMMUNITY OF CHILDREN SUFFERING ULCER DUODENUM
https://doi.org/10.25207/1608-6228-2017-24-4-109-114
Abstract
Aim. To explore some regularities of the immune system and resistance in children with ulcer duodenum. On the basis of systemic pathogenetic approach to develop a system of integrated assessment of the immunity of the child with the ulcer duodenum.
Materials and methods. A clinical and immunological study of 114 children aged 5-14 years, suffering from an ulcer duodenum. The control group consisted of 30 healthy children of similar age. Investigation of venous blood were performed on the day after admission and after a course of appropriate treatment before discharge. By mathematical analysis of unsubstantiated "factor" structure of the immune system in normal and ulcer duodenum.
Results. At different stages of the disease varies the amount and structure of relations between the components within the immune system and its relationship with other systems. Conclusion. These peculiarities – a normal physiological response of the immune system to develop an immunological process in the mucosa of duodenum.
About the Authors
A. V. PolyanskiyRussian Federation
Corresponding author: Alexei V. Polyanskiy
58, 2-nd passage Shevchenko Street, Krasnodar, 350001; tel.: 8-903-4-111-340
A. V. Burlutskaya
Russian Federation
4 Sedina Street, Krasnodar, 350063
References
1. Zemskov A.M., Zemskov V.M., Esaulenko I.E., Zemskov M.A., Thin R.V., Zlokhodov V.I. New principles of evaluation and correction of immunological disorders. – Moscow: "Triada-X", 2008. 336 p. (In Russ.).
2. Kolkhir P.V. Evidence-based allergology-immunology. – Moscow: Practical medicine, 2010. 528 p. (In Russ.).
3. Mail, D. Immunology. – Moscow, Logosfera, 2007. 568 p.
4. Zaichik A.Sh., Churilov L.P. General pathophysiology. – St. Petersburg: ELBI, 2007. 624 p. (In Russ.).
5. Novikov DK, Novikov P.D. Clinical immunopathology. Leadership. M.: Med. Lit., 2009. 464 p. (In Russ.).
6. Ross G.D. Identification of human lymphocyte subpopulations by surface marker analysis. Blood.1979; 53: 779-811.
7. Manchini G., Carbonara A., Heremans J. Immunochemical quantitation of antigens by single radial immunodiffusion. Immu¬nochemistry. 1965; 2(3): 235-254.
8. Kozlov L.V., Vavilova L.M., Golosova Т.V. The Micromethod of the Determination of Complement Factors. Immunology. 1985; 3: 66-68.
9. Venglinskaya EA, Mazhara N.F. A method for studying the phagocytic function of blood microphages in laboratory animals us¬ing the NST test. Invention and rationalization in medicine. – M., 1987. 135 p.
10. Loida Z., Goserau R., Shibler T. Histochemistry of enzymes, laboratory methods. – M., 1982. 271 p. (In Russ.).
11. Venglinskaya E.A., Rukavtsov B.I., Shubich M.G. Fluores¬cence-cytochemical detection of free cytoplasmic cationic protein in blood leukocytes. Laboratory business. 1976; 5: 270 -273.
12. Shubich M.G. Cytochemical determination of leukocyte alkaline phosphatase. Laboratory business. 1965; 6: 10-14.
13. Khachaturov E.N., Smirnova E.A. Application rivanol-SO2 for DNA cytofluorimetry. Izvetstia. ANSSSR. Series Biologi. 1966; 6: 900-905.
Review
For citations:
Polyanskiy A.V., Burlutskaya A.V. OPPORTUNITIES AND PROSPECTS OF THE SYSTEM INTEGRATED ASSESSMENT OF IMMUNITY OF CHILDREN SUFFERING ULCER DUODENUM. Kuban Scientific Medical Bulletin. 2017;(4):109-114. (In Russ.) https://doi.org/10.25207/1608-6228-2017-24-4-109-114