CLINICOPATHOLOGIC CRITERIA OF PERINATAL BRAIN INJURY IN CHILDREN BORN WITH LOW AND EXTREMELY LOW BODY WEIGHT
https://doi.org/10.25207/1608-6228-2017-24-4-176-180
Abstract
Aim. The objective of this study was to establish structural changes in the brain of preterm neonates born with low and extremely low body weight, with perinatal brain damage of moderate severity by neurotractography.
Materials and methods. 48 children born with very low and extremely low body weight were examined. Structural changes according to neurosonography were revealed in all. Neurotractography was performed before discharge from the nursing department.
Results. A significant difference in the neurological status before discharge was not detected in children. The area of interest was the crus posterius capsulae internae during neurotractography. Reduction of FA and increase of ADC was detected in three cases. These children had a motormental retardation at the adjusted age of 12 months.
Conclusions. Neuropathography results can increase the accuracy of later neurologic prognosis. If significant changes in the neurotractography are not recorded, then a favorable neurological prognosis is predicted
About the Authors
M. P. Yakovenko
Kuban State Medical Umiversity of the Ministry of Health Care of the Russian Federation
Russian Federation
Russian Federation
Department of Pediatrics with the course of neonatology FPD and PRS
Corresponding author: Margarita P. Yakovenko
4 Sedina Street, Krasnodar; tel.: 8(961) 585-43-53
E. I. Kleshenko
Kuban State Medical Umiversity of the Ministry of Health Care of the Russian Federation
Russian Federation
Russian Federation
Department of Pediatrics with the course of neonatology FPD and PRS
4 Sedina Street, Krasnodar
References
1. Teberdieva S.O., Ushakova L.V., Filippova E.A., Bychenko V.G., Dorofeeva E.I., Burov A.A., Degtyarev D.N. Diagnostic value of neuroimaging techniques in newborn infants with malformations of internal organs. Rossiiskii vestnik perinatologii i pediatrii. 2017; 62(1): 47–52. (In Russ., English abstract). DOI: 10.21508/10274065-2017-62-1-47-52
2. Volodin N.N. Neonatologiya: natsional'noe rukovodstvo. Kratkoe izdanie. Moscow: GEOTAR-Media, 2014. – 896 p. (In Russ.)
3. Baĭbarina E.N., Filippov O.S., Guseva E.V. The results of development of an obstetric service in the Russian Federation and the measures for its improvement. Rossiyskiy vestnik akushera-ginekologa. 2014; 14: 4–8. (In Russ., English abstract)
4. Grebennikova O.V., Zavadenko A.N., Rogatkin S.O., Medvedev M.I., Degtiareva M.G. Clinical and neurophysiological objectification and evaluation of treatment efficacy in children with perinatal hypoxic-ischemic injury of the CNS. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2014; 114 (4-1): 63–67. (In Russ., English abstract)
5. Zavadenko A. N., Degtyareva M.G., Medvedev M.I., Rogatkin S.O., Grebennikova O.V. Clinical and neurophysiological follow up pf children different gestation age with neonatal seizures. Pediatria. 2017; 1: 23–28. (In Russ., English abstract)
6. Timofeeva L.A., Ryumina I.I., Ionov O.V., Degtyareva A.V., Zubkov V.V., Kan N.E., Degtyarev D.N., Sharafutdinova D.Rpecific features of neonatal adaptation and postnatal development of infant born at 340/7–366/7 weeks’ gestation. Akusherstvo i Ginekologiya/ Obstetrics and Gynecology. 2017; 1: 72–76. (In Russ., English abstract)
7. Fedorova L.А. Psychomotor development and rehabilitation methods in preterm infants after discharge. Bulletin of Contemporary Clinical Medicine. 2014. 7(6): 62–63. (In Russ., English abstract)
8. Prusakov V.F., Morozova E.A., Belousova M.V., Utkuzova M.A., Zaikova F.M., Marulina V.I., Gamirova R.G., Morosov D.V. Actual problems of perinatal neurology. Practical medicine. 2012; 2: 57–60. (In Russ., English abstract)
9. Guseva E.I., Konovalova A.N., Skvortsovoy V.I., Gekht A.B. Nevrologiya: natsional'noe rukovodstvo. Moscow: GEOTARMedia; 2009. 1040 p. (In Russ.).
10. Abdelsalam E., Gomaa M., and Elsorougy L. Diffusion tensor imaging of periventricular leukomalacia – Initial experience. The Egyptian Journal of Radiology and Nuclear Medicine. 2014; 45(4): 1241-1247.
11. Dudink J., Counsell S., Lequin, M. and Govaert, P. DTI reveals network injury in perinatal stroke. Archives of Disease in Childhood – Fetal and Neonatal Edition. 2011; 97(50): 362-364.
12. Müller H., Unrath A., Huppertz H., Ludolph A., Kassubek J. Neuroanatomical patterns of cerebral white matter involvement in different motor neuron diseases as studied by diffusion tensor imaging analysis. Amyotrophic Lateral Sclerosis. 2012; 13(3):254-264.
Review
For citations:
Yakovenko M.P., Kleshenko E.I. CLINICOPATHOLOGIC CRITERIA OF PERINATAL BRAIN INJURY IN CHILDREN BORN WITH LOW AND EXTREMELY LOW BODY WEIGHT. Kuban Scientific Medical Bulletin. 2017;(4):176-180. (In Russ.) https://doi.org/10.25207/1608-6228-2017-24-4-176-180
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