CHANGE IN THROMBOELASTROMETRY AND PLASMA HEMOSTASIS PARAMETERS IN WOMEN IN OBSTETRIC PRACTICE
https://doi.org/10.25207/1608-6228-2017-24-5-54-58
Abstract
Aim. To study changes in the parameters of thromboelastometry and hemostasis system coagulation component in women with uncomplicated pregnancy and women with manifestations of thrombophilia in the perinatal period.
Materials and methods. The analysis of thromboelastometry and coagulogram parameters of 408 women was conducted. The subjects were conventionally divided into following groups: A - women without pathology of hemostasis (n=152), B – women with clinical manifestations of thrombophilia (n=256). The examination was carried out at various times of the perinatal period.
Results. In patients with thrombophilia, significant changes in coagulation potentials, characterized by hypercoagulation, thrombinemia and a decrease in the reserve of natural anticoagulants, and a decrease in fibrinolysis activity were noted. The most significant changes in hemostasiological parameters were indicated in the process of labor.
Сonclusion. The studied parameters of coagulogram and thromboelastometry should be used in assessing the risk of thrombotic complications and the rationale for antithrombotic therapy.
About the Author
A. Y. MURATOVA
Federal State Autonomous Educational Institution of Higher Education "North-Caucasian Federal University"
Russian Federation
Russian Federation
Pushkin str. 1, building 3, Stavropol, Russia, 355000
tel.: +7 (962) 454-90-42; 5, Artema, str., Stavropol, Russia, 355017
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Review
For citations:
MURATOVA A.Y. CHANGE IN THROMBOELASTROMETRY AND PLASMA HEMOSTASIS PARAMETERS IN WOMEN IN OBSTETRIC PRACTICE. Kuban Scientific Medical Bulletin. 2017;(5):54-58. (In Russ.) https://doi.org/10.25207/1608-6228-2017-24-5-54-58
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