The article provides an analysis of the regulatory framework of the Eurasian economic union (the Union) to ensure the quality and safety of food products. In accordance with the Agreement on the Eurasian economic union, which entered into force on 01.01.2015 (hereinafter referred to as the Agreement), in order to ensure the sanitary and epidemiological welfare of the population within the Union to pursue a coordinated policy in the sphere of application of sanitary and phytosanitary measures. In accordance with the Agreement of the Customs Union «On common principles and rules of technical regulation in the Republic of Belarus, Kazakhstan and the Russian Federation» dated 18 November 2010 to the products to which the Union set mandatory requirements on technical regulation, attributed also to food products. Regulations approved by the food safety technical regulations. In accordance with the Agreement in the technical regulations of the Customs Union established requirements for the product or to the processes of production, storage, transportation, marketing and utilization, as well as the identification rules, forms, diagrams, and assessment procedures (confirmation) of compliance of food products. In order to ensure the sanitary-epidemiological, veterinary and phytosanitary welfare within the Union pursue a coordinated policy in the sphere of application of sanitary and phytosanitary measures. The necessity of improving the system of regulation of the quality and safety of food products through the development and introduction of the development, approval, modification and application of common sanitary and epidemiological and hygienic requirements and procedures to ensure the quality and safety of food products. Also shown that the implementation of standards adopted by the Agreement of the Union, taking into account international experience, based on the basic WTO agreements and international standards, sanitary and phytosanitary measures, as well as experience and scientific and technical capabilities of the Member States of the Union will create in the Union a coherent, consistent, transparent, knowledge-based, dynamic system of legal regulation in the sphere of food products. The solution to this problem, along with an increase in the quality and safety of food products, will increase export potential and investment attractiveness of the food producers in the member states of the Eurasian Economic Union.

To develop a working classification of traumatic spinal stenosis for injuries of the lower thoracic and lumbar spine. 170 patients with injuries of the lower thoracic and lumbar spine accompanied by traumatic spinal stenosis for 20052013. Decompressive-stabilizing operations with PSF were done for all patients. Priority was given to reposition indirect decompression. The dependence of the efficiency of the reformation of the spinal canal stenosis by morphological reasons was studied. This classification allows to predict for PSF the effectiveness of the reposition of the dural sac decompression by stretching ligaments. Reposition and decompression are most effective when compression of the dural sac by a single bone fragment back of the vertebral body or two large fragments without reversion to 10 days after injury, or if subluxation and dislocation in the early and intermediate periods of spinal cord injury.

In the article describes the experience of the treatment of burns dorsum of the hand in the burn center GBUZ NII - KKB № 1 them. prof. Ochapovsky. Spend structure, frequency analysis, incidence and types of surgical treatment of burns dorsum of the hand. To optimize the method of early necrectomy primary plastics provides a method of non-perforated skin autografts after necrectomy held under the harness, which reduces the operation time and reduce intraoperative blood loss. Due to the plastic of non-perforated autografts in postpoerative period there is a positive not only functional, but also cosmetic result.

Within our study we compared the effectiveness of laparoscopic myomectomy with bed unit closure with individual sutures and a monofilament self-locking thread. Depending on the way of the uterine wall closure during laparoscopic myomectomy 2 groups were formed among 40 women: in group I (n = 20) a monofilament synthetic thread of poliglecaprone (Monocryl Plus 0) was used by individual Z-shaped sutures; in group II (n = 20) a node-free uninterrupted suture was used with the thread with a serrated design and a fixing loop (V-lock 180 «0»). Using a node-free suture in laparoscopic myomectomy helped to reduce the duration of suturing the myometrium defect, the intraoperative blood loss, general surgical risks and the complexity of the intervention. Certain clinical benefits in using barbed suture V-lock were identified: the formation of a well-fixed uterine scar due to full recovery of the uterus anatomy after laparoscopic myomectomy while minimizing intra- and postoperative complications.

It was found that during the experiments on rats assisted by the Doppler flowmetering method the benzofurocainum (BF) lowers the erythrocyte flow and its fluctuation in the capillary race of the attached gum (AG) of the lower incisors by the intraperitoneal introduction in the dosage of 10 mg/kg in conditions of sound parodentium during 40 min (most evidently on the 10th min). In addition the vasomotor activity remains stable in comparison with the initial one, that can be conditioned by the increase of the general peripheric vessel resistance. In conditions of experimental periodontitis (EP) the blood microcirculation (BMC) in AG undergoes essential changes to lowering. The use of the traditional medicamental therapy (TMT) against the background of EP causes the increment in BMC in the chosen area after 12 days of treatment; one month later BMC decreases. The combination ТМТ + BF in taken conditions of the experiment induces the increment in BMC immediately after the treatment as well as one month after the use, besides BMC reaches the initial level.

In the present study we have investigated influence of SS-68, which has been previously demonstrated to produce potent antiarrhythmic effects in mammalian myocardium, on the electrophysiological effects of selective M3 cholinoreceptors stimulation in rat atrial myocardium. M3 receptors were activated with muscarinic agonist pilocarpine (10 jM) in the presence of highly selective blocker of M2 cholinoreceptors methoctramine (100 nM). In isolated left atrial preparations M3 stimulation produced reduction of action potential duration by 20 ± 2,2% of control duration. SS-68 (10 jM) decreased intensity of action potential shortening more than twice - to 7,9 ± 1,1% of control action potential duration. SS-68 also suppressed action potential shortening produced by pilocarpine in the absence of M2 antagonist. Thus, compound SS-68 attenuates effect of joint activation of M2 and M3 receptors as well as the effect of selective M3 stimulation.

Developed surgical methods of surgical treatment of deep burns, creating conditions for engraftment full thickness transplant on purulent wound. Studied the pathological aspects of the wound bed after excision of granulation and wound edges during engraftment full thickness transplant in 5 patients. Investigations of the fibrous layer of granulation tissue.

Smoking is one of the most pressing public health problems. Despite numerous antismoking campaigns, the proportion of women smokers is not decreasing. Smoking during pregnancy has an adverse influence on the physiological course of pregnancy and on the fetus and newborn. It has been proven that tobacco smoke is detected about 4 thousand different chemical compounds, of which 200 are the most toxic. Therefore the fetus develops in conditions of chronic hypoxia and is subjected to a toxic effect of constituents of tobacco smoke. In this connection there is a need to investigate the condition of the skin microcirculation with early pregnancy. At the present time, wide implementation in practice of doctors of various specialties, including obstetricians and gynecologists, the method of laser doppler flowmetry.

The research objective is an assessment of effectiveness of hyperbaric re-respiration (HRR) in treatment of military servicemen suffering from chronic abacterial prostatitis (CAP). The research type is prospective (cohort), clinical and physiological. The subjects are 38 patients with CAP in the acute phase (category III A and III B), aged 32-46, were randomly allocated into 3 groups depending on the kind of therapy: the control group - conventional treatment of CAP in the acute phase (n = 10); the comparison group (n = 14) - traditional therapy and 12-14 hyperbaric oxygen therapy treatments (35-40-minute stay in the oxygen chamber at a pressure of about 153 kPa); the treatment group (n = 14) - the traditional therapy and a course of HRR (12-14 treatments, 35-40 minute stay under the conditions of higher oxygen (27.9 kPa) and carbon dioxide (3.4 kPa) partial pressure produced in the pressure chamber at a total pressure of about 153 kPa). All patients before treatment, after his graduation, and then six months later determined the indices of phagocyte activity of neutrophils, which are judged on the state of nonspecific resistance. Initial examination revealed a clear shortage of nonspecific protective mechanisms in most patients. Spent treatment accompanied by statistically significant increases in aerobic and anaerobic phagocyte activity only in patients of the treatment group that has resulted in significant inter-group differences of the studied parameters. Through 6 months in patients of the treatment group registered a further increase in the activity of aerobic and anaerobic mechanisms of phagocytosis in the absence of such trends in the other two groups. Therefore, the appointment of HRR promotes activation of nonspecific resistance mechanisms in patients with CAP, which contributes to extension of relapse-free period in the course of the disease.

The article describes the use of techniques bioimpedancmetria and heart rate variability (HRV) among young people to identify early functional changes in the composition of the composite body and the vegetative regulation of heart rhythm associated with physical activity (PA), body weight and stress. Determined a high prevalence of low PA (45,2%), overweight and obesity (41,0%). The level of visceral fat is an early indicator of overweight and obesity, low PA, high levels of stress and increased sympathetic activity of the autonomic nervous system.

The study involved 1940 people living in the territory of the Republic of North Ossetia - Alania, in the age of 20-74 years. The work studied the prevalence of one of the major controllable risk factors for coronary heart disease (hypertension) in the population of the region. A comparative analysis of the prevalence of hypertension according to sex, age and type of settlement (town, village). As expected, the minimum percentage of patients with hypertension were identified among the younger age group (20-44 years) in each subsequent five-year period the number of people suffering from hypertension, increased. The maximum number of hypertensive patients was diagnosed at the age of 60-74 years. In most cases, higher numbers of blood pressure were recorded among respondents living in the city.

Using the combined of L-arginine with inhibitors of HMG-Co-A reductase simvastatin, atorvastatin, rosuvastatin and rosuvastatin nanopartikulirovannym on background modeling endotoxin-induced disease, the introduction of strain 603 Staphylococcusaureus shows endotelio- and cardioprotective effects, manifested in preventing the proliferation coefficient of endothelial dysfunction (CED), adrenoreactivity, maintaining myocardial reserve and the normalization of the values of biochemical markers (Total NO, expression of eNOS, C-reactive protein, IL-6, TNF). Thus, combination therapy was so effective, that the values obtained in the combination therapy did not differ from those derived from control animals.

Results of treatment of 55 patients after repeated reconstructive surgeries on the colon. 87.3% of the patients were elderly. More than half of all the benefits of reconstruction was performed after surgery for colon cancer complicated and complicated diverticular disease. «End to side» preference was given to colonic anastomosis. The failure of intestinal suture occurred in 4 patients (7.3%), mortality was 1.8%.

The work offers a view on the results obtained from a radiological and morphometric study of native preparations obtained from 43 passported skulls with physiological occlusion and normodontia of permanent teeth under neutral position of the jaws and a neutral type of gnathic facial skull. It was found that in patients with physiological occlusion of permanent teeth, skulls with neutral type of gnathic facial part of the cranium as well as neutral jaw relationships proved to be predominant, while the major parameters of the dentofacial arches are determined through mesial-distal diameters of the teeth.

Results of research of a condition of mineral density of a bone tissue at men with cirrhosis are presented in this article. Results of the conducted research showed high prevalence osteosinging at the men sick with cirrhosis, in comparison with data of control group. Influence the etiologicheskikh of factors and degree of hepatocellular insufficiency on expressiveness of an osteopenichesky syndrome at the examined patients is also noted.

We investigated the relative expression of genes responsible for the estrogen reception and metabolism - CYP1A 1, CYP1A 2, CYP1B 1, CYP19A, ESR1, ESR2, GPER, STS, SULT1A and SULT1E1 - by real-time PCR in tumor and conditionally healthy uterine tissues of 27 female patients in Southern Russia aged 38-72 years with histologically confirmed diagnosis of uterine cancer. It is found that transcription activity of these genes during malignancy of uterine tissues depends of female patients age and the stage of tumor cells differentiation. It is potentially allow to use investigated genes as biomarkers of uterine tissues malignancy with considering age features of female patients and stages of cancer process development.

The article is devoted to the experience of the introduction and use of medical information systems in the outpatient. Analyzed some organizational and methodological problems of implementation of information exchange.

The article describes the complexity of modern theoretical and practical approaches to the understanding of mental health and disease. Nozotsentrichesky and normotsentrichesky approaches are analyzed. The possibility of the use of general medical criteria dichotomy «norm/pathology» is discussed. From the standpoint of the modern paradigm of biopsychosocial unity of man analyzes the specificity criteria of mental norms of social and ethnocultural conditions. It describes the current criteria for the analysis - the presumption of mental health.

The results of the diagnosis and treatment of chronic catarrhal pharyngolaryngitis accompanied by dysphonia with chronic odontogenic sinusitis. All under the supervision there were 65 residents of the Stavropol territory, chronic odontogenic sinusitis pharyngolaryngitis and who were examined and treated in the Stavropol regional clinical hospital. The results showed that chronic inflammatory diseases of the paranasal sinuses frequent cause of diseases of the pharynx and larynx. The authors emphasize that odontogenic sinusitis are not amenable to conservative treatment and are characterized as long-flowing. Treatment of these patients is effective only when the complex diagnosis and joint actions ENT doctor and dentist.

During present research, 216 patients with external genital endometriosis were examined. Examined women had been suffering from complaints (pelvic pain, dyspareunia, psycho-emotional disorders) from 1.5 to 19 years. The influence of these methods of rehabilitation was monitored on parameters of life quality and intensity of pain before and after treatment. Therapy included use of dienogest 2 mg or ethynilestradiol 30 mсg/dienogest 2 mg with or without radonotherapy. Positive effects of all three methods were revealed. After treatment amount of women, still complaining of pelvic pain reduced to 12.0-30.6%. In comparison application of dienogest 2 mg and radon appears to be more effective.

The article is devoted to development of a mathematical model construction of dentition in complete dentures, based on the median between alveolar lines and angles for posterior teeth relative to the total alveolar arc. Get digital values of the standard deviation between alveolar lines for different types of atrophy of the alveolar ridges of edentulous jaws.

To assess the degree of upper uric tracts normalization, which is key for cure of ureter hydronephrosis of various genesis, we used the ureterectasia rate (UR). The necessity in its calculation is imperative due to the absence of evident tests, which enable to assess the rate of megaloureter reduction. Immediate ureter normalization just after removing the causes of ureter dysfunction, especially in case of its obstructive form, is impossible. Absolute figures of ureter diameter are unobjective, as they do not take into account child's stature, which is essential in the fist year of life.

Research objective - to study influence of influence of the highest frequencies on biologically active points for the purpose of stimulation of a fagotsitoz at patients with a chronic generalized periodontal disease of varying severity and acceleration of recovery. 160 patients with a chronic generalized periodontal disease took part in research. Average age of patients made 30 (25; 35) years. When studying indicators of a fagotsitoz the following indicators were defined: activity and intensity of a fagotsitoz of neutrophils of peripheral blood it was estimated on a fagotsitarny index and fagotsitarny number. Activity of oxygen-containing systems of neutrophils was estimated on reaction of restoration nitroblue a tetrazoliya spontaneous and stimulated the zimozany. As pathogenetic therapy used the highest frequencies in number of 10 sessions on biologically active points of face skin. In the course of research it is established that patients a chronic generalized periodontal disease have a restoration of indicators of a fagotsitoz. Results of research can be applied in complex treatment of patients with a generalized periodontal disease.

In the article the results of examination of some immune characteristics, including some autoantibodies in 28 children with chronic constipation are represented. Increased levels of circulating immune complexes and increased spontaneous NST test were the most common immune laboratory findings. ANCA were found in 18 patients. There were no correlation between the type of constipation (dolichosigmoid, anal athresia, functional constipation), severety and character of disbiosis and ANCA rates. Thus, in most cases revealed immune disorders may indicate chronic inflammation in the bowl associated with chronic constipation. Children with increased ANCA rates seems have the higher risk of autoimmune disorders in future

Hardware and software system, which makes it possible to visualize the glow center, marker of the excitation center in tissue, in the electric field, is created. The system was tested in 14 experiments with sinoatrial nodes of cat's hearts, which's fist excitation's center is in the depth of the right auricle's myocardium, and in 30 experiments with frog's venous sinuses, which's first excitation's center is situated in the superficial layer of the sinus wall. Also observations were held with deeply situated center - in cat's tooth's pulp, which is surrounded by insulators: dentine and tooth's enamel. The ability of visualization the excitation's center was developed at localizations in different depths.

The aim of the work was to study the characteristics of anxiety and depressive disorders in medical students. There have been continuous cross-sectional complex clinical and epidemiological, clinical and psychopathological examination of 976 students of the first and fifth courses of all faculties. The main methods used in clinical and epidemiological, clinical, psychopathological, statistical methods. As a screening tool used by Hospital Anxiety and Depression Scale HADS. The prevalence of anxiety and depressive disorders of different nosology among medical students was 6.8% in the first year and 11.5% - in the fifth, with a prevalence of clinically significant anxiety in the first year and a significant prevalence of clinically significant depression in fifth, with a predominance of girls.

The results of surgical treatment of 72 patients with genitals prolapse are presented. Reasonability of the use of mesh transplants for genitals prolapse correction is showed. You can see the comparative characteristic of quality of patients life after prolapse correction with the use of mesh transplants and of the own tissues.

A retrospective study of immediate and gave-represented results of surgical treatment of 112 patients with acute cholecystitis combined with gastric ulcer and/or duodenal ulcers who were treated in surgical departments in Krasnodar city hospital ambulance (SCC emergency hospital) from 2010 to 2015.

It was found that the incidence of alcohol-related diseases with fatal intoxications with ethanol on the background of the various forms of alcoholic liver disease is variable and is prevalent in the groups alcoholic hepatitis and steatosis.

The article analyzed 43 cases of hematological diseases identified in patients with middle and old age, were treated in the regional hospital for war veterans. We discuss the identification of the most typical symptoms of various blood diseases, diagnostic difficulties and the algorithm of differential diagnosis. The study revealed the clinical features of hematological malignancies in the elderly.

The analysis of results of treatment of 67 patients underwent surgical treatment for about thyroid nodules. Patients were divided into two groups. Patients of the first group performed traditional hemithyroidectomy. Second-Videoassisted hemithyroidectomy (MIVAT), which resulted in a significant decrease in the intensity and duration of pain, better cosmetic effect, reduce the period of post-operative recovery and rehabilitation.

The article presents the characteristics of the formation processes of the contingent of disabled people with mental illnesses in a large city for the 15-years period of time. The parallels between the prevalence of mental illnesses and disability are given. The sociological research of a lifestyle and social position of 640 disabled persons with mental illness was conducted.

The main problems of neonatal period is infectious pathology. A special place among which is an infection of the urinary system, the incidence of 23%. The main source for infectious pathologies of newborn is the mother. The article presents pharmacoeconomic assessment of complications during pregnancy and their impact on the rise in children with neonatal infections over the urinary system.

In the article materials are presented about participation of Kuban medical Institute the name of Red Army, his employees, graduating students and students in Great Patriotic war. Оur institute did not close at the years of war. More than one and a half thousand our physicians treated and rescued injured on all fronts, in guerrillas, in an underground and frightful fascist captivity.

The article provides an overview of the domestic and foreign literature on the etiology and pathogenesis of sensorineural hearing loss.